Catalytic cleavage activities of 10–23 DNAzyme analogs functionalized with an amino group in its catalytic core
Functionalization of the catalytic loop of 10–23 DNAzyme with an amino group was performed by incorporation of 7-(3-aminopropyl)-8-aza-7-deaza-2′-deoxyadenosine in different single positions. Among the nine modified positions in the catalytic loop, A9 is the unique position with positive contributio...
Main Authors: | Qi Wang, Di Zhang, Maosheng Cheng, Junlin He, Keliang Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2012-02-01
|
Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221138351100102X |
Similar Items
-
Studies on the Two Thymine Residues in the Catalytic Core of 10-23 DNAzyme: The Impact on the Catalysis of Their 5-Substituted Functional Groups
by: Pengyu Li, et al.
Published: (2017-06-01) -
Catalytic Activities of Multimeric G-Quadruplex DNAzymes
by: Raphael I. Adeoye, et al.
Published: (2019-07-01) -
Catalytic Activities of Ribozymes and DNAzymes in Water and Mixed Aqueous Media
by: Shu-ichi Nakano, et al.
Published: (2017-11-01) -
Optimization study of the catalytic activity of DNAzymes based on telomeric G-quadruplexes
by: Kosman Joanna, et al.
Published: (2012-04-01) -
DNAzyme conjugated nanomaterials for biosensing applications
by: Gong Liang, et al.
Published: (2014-10-01)