INTERMITTENT ANTIARYTHMIC THERAPY OF ARIOVENTICULAR NODAL REENTRY TACHYCARDIA IN CHILDREN

• Main Authors: Boris Djindjic, Ljiljana Pejcic, Bojko Bjelakovic, Miodrag Stojanovic, Ljiljana Bjelaković, Danka Sokolovic
• Format: Article
• Language: English
• Published: University in Nis, Faculty of Medicine 2008-04-01
• Series: Acta Medica Medianae
• Subjects: antiarrhythmic drugs; atrioventricular tachycardia; children
• Online Access: http://publisher.medfak.ni.ac.rs/2008-html/2-broj/INTERMITTENT%20ANTIARRHYTHMIC%20....pdf

Until recent advances in pharmacology and clinical cardiology regarding farmacodynamics of antiarrhythmic drugs and their efficiency in patients with refractory paroxysmal supraventricular tachycardia, chronic prophylactic therapy was the only treatment option for patients refusing catheter ablation. Another treatment option, also known by eponym “pill in pocket” have been shown to be equally useful and efficacious.The aim of our study was prospective examination of children with refractory atrioventricular nodal reentry tachycardia (AVNRT) who were withdrawn from chronic antiarrhythmic prophylactic therapy and started with intermittent oral beta blocker treatment (propranolol at dosage 1 mg/kg - max 80 mg).Twelve children (8 boys and 4 girls) with AVNRT were included in the study. Four children did not have arrhythmia during first six months after withdrawal and 7 were successfully treated without complication.Intermittent antiarrhythmic therapy in children with AVNRT could be very efficacious and useful treatment option which significantly improves their quality of life.