Direct activation of ATM by resveratrol under oxidizing conditions.
Resveratrol has been widely reported to reduce cancer progression in model systems and to selectively induce cell death in transformed cell lines. Many enzymes have been reported to respond to resveratrol in mammalian cells, including the Ataxia-Telangiectasia Mutated (ATM) protein kinase that acts...
Main Authors: | Ji-Hoon Lee, Zhi Guo, Logan R Myler, Suting Zheng, Tanya T Paull |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4059639?pdf=render |
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