Nelfinavir and other protease inhibitors in cancer: mechanisms involved in anticancer activity [v2; ref status: indexed, http://f1000r.es/536]

Objective: To review the mechanisms of anti-cancer activity of nelfinavir and other protease inhibitors (PIs) based on evidences reported in the published literature. Methods: We extensively reviewed the literature concerning nelfinavir (NFV) as an off target anti-cancer drug and other PIs. A classi...

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Bibliographic Details
Main Author: Tomas Koltai
Format: Article
Language:English
Published: F1000 Research Ltd 2015-03-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/4-9/v2