Anticancer Activity of γ-Bisabolene in Human Neuroblastoma Cells via Induction of p53-Mediated Mitochondrial Apoptosis

Anticancer Activity of γ-Bisabolene in Human Neuroblastoma Cells via Induction of p53-Mediated Mitochondrial Apoptosis

γ-Bisabolene has demonstrated antiproliferative activities against several human cancer cell lines. This study first discloses the antiproliferative and apoptosis induction activities of γ-bisabolene to human neuroblastoma TE671 cells. A CC50 value of γ-bisabolene was 8.2 μM to TE671 cells. Cell cyc...

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Bibliographic Details
Main Authors: Yu-Jen Jou, Chun-Hung Hua, Chen-Sheng Lin, Ching-Ying Wang, Lei Wan, Ying-Ju Lin, Su-Hua Huang, Cheng-Wen Lin
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Molecules
Subjects:
γ-bisabolene
neuroblastoma
anticancer
apoptosis
p53
CK2α
Online Access:http://www.mdpi.com/1420-3049/21/5/601

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http://www.mdpi.com/1420-3049/21/5/601

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