Bone Sclerostin and Dickkopf-related protein-1 are positively correlated with bone mineral density, bone microarchitecture, and bone strength in postmenopausal osteoporosis

Bone Sclerostin and Dickkopf-related protein-1 are positively correlated with bone mineral density, bone microarchitecture, and bone strength in postmenopausal osteoporosis

Abstract Background Wnt-catenin signaling antagonists sclerostin and dickkopf-related protein-1 (Dkk-1) inhibit bone formation and are involved in the pathogenesis of postmenopausal osteoporosis (PO). However, the association between sclerostin and Dkk-1 and bone mineral density (BMD) in women with...

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Bibliographic Details
Main Authors: Jia Peng, Zhang Dong, Zhang Hui, Wang Aifei, Deng Lianfu, Xu Youjia
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Musculoskeletal Disorders
Subjects:
Sclerostin
Dickkopf-related protein-1
Postmenopausal osteoporosis
Bone mineral density
Bone microarchitecture
Bone strength
Online Access:https://doi.org/10.1186/s12891-021-04365-8

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