Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways
Salidroside (Sal) is an active ingredient that is isolated from Rhodiola rosea, which has been reported to have anti-inflammatory activities and a renal protective effect. However, the role of Sal on renal fibrosis has not yet been elucidated. Here, the purpose of the current study is to test the pr...
Main Authors: | Rui Li, Yujuan Guo, Yiming Zhang, Xue Zhang, Lingpeng Zhu, Tianhua Yan |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-03-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/20/5/1103 |
Similar Items
-
Salidroside alleviates lipotoxicity-induced cell death through inhibition of TLR4/MAPKs pathway, and independently of AMPK and autophagy in AML-12 mouse hepatocytes
by: Xiaobing Dou, et al.
Published: (2020-02-01) -
Salidroside Regulates Inflammatory Response in Raw 264.7 Macrophages via TLR4/TAK1 and Ameliorates Inflammation in Alcohol Binge Drinking-Induced Liver Injury
by: Peng Sun, et al.
Published: (2016-11-01) -
Salidroside inhibits MAPK, NF-κB, and STAT3 pathways in psoriasis-associated oxidative stress via SIRT1 activation
by: Fengli Xu, et al.
Published: (2019-01-01) -
Salidroside protects against foam cell formation and apoptosis, possibly via the MAPK and AKT signaling pathways
by: Jing Ni, et al.
Published: (2017-10-01) -
An Approach to Characterizing the Complicated Sequential Metabolism of Salidroside in Rats
by: Zhiqiang Luo, et al.
Published: (2016-05-01)