NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages

Toxoplasma infections in humans and other mammals are largely controlled by IFN-γ produced by the activated adaptive immune system. However, we still do not completely understand the role of cell-intrinsic functions in controlling Toxoplasma or other apicomplexan infections. The present work identif...

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Bibliographic Details
Main Authors: Sumit K. Matta, Kelley Patten, Quiling Wang, Bae-Hoon Kim, John D. MacMicking, L. David Sibley
Format: Article
Language:English
Published: American Society for Microbiology 2018-08-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.01393-18

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