NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages
Toxoplasma infections in humans and other mammals are largely controlled by IFN-γ produced by the activated adaptive immune system. However, we still do not completely understand the role of cell-intrinsic functions in controlling Toxoplasma or other apicomplexan infections. The present work identif...
Main Authors: | Sumit K. Matta, Kelley Patten, Quiling Wang, Bae-Hoon Kim, John D. MacMicking, L. David Sibley |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2018-08-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.01393-18 |
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