Design, Synthesis and DNA Interaction Study of New Potential DNA Bis-Intercalators Based on Glucuronic Acid

A series of novel potential DNA bis-intercalators were designed and synthesized, in which two glucuronic acids were linked by ethylenediamine, and the glucuronic acid was coupled with various chromophores, including quinoline, acridine, indole and purine, at the C-1 position. The preliminary binding...

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Bibliographic Details
Main Authors: Jiuyang Zhao, Wei Li, Rui Ma, Shaopeng Chen, Tao Jiang, Sumei Ren
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/14/8/16851

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