Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles.

Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles.

Transmission of prions between species is limited by the "species barrier," which hampers a full characterization of human prion strains in the mouse model. We report that the efficiency of primary transmission of prions from Creutzfeldt-Jakob disease patients to a wild rodent species, the...

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Bibliographic Details
Main Authors:	Romolo Nonno, Michele A Di Bari, Franco Cardone, Gabriele Vaccari, Paola Fazzi, Giacomo Dell'Omo, Claudia Cartoni, Loredana Ingrosso, Aileen Boyle, Roberta Galeno, Marco Sbriccoli, Hans-Peter Lipp, Moira Bruce, Maurizio Pocchiari, Umberto Agrimi
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2006-02-01
Series:	PLoS Pathogens
Online Access:	https://doi.org/10.1371/journal.ppat.0020012

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