Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature

Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature

Longitudinal imaging of bone marrow would shed insight into long-term cellular dynamics within this compartment. Here, the authors develop a multi-photon imaging approach for the mouse femur and reveal extensive vascular plasticity within the bone marrow during bone healing and steady-state homeosta...

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Main Authors: David Reismann, Jonathan Stefanowski, Robert Günther, Asylkhan Rakhymzhan, Romano Matthys, Reto Nützi, Sandra Zehentmeier, Katharina Schmidt-Bleek, Georg Petkau, Hyun-Dong Chang, Sandra Naundorf, York Winter, Fritz Melchers, Georg Duda, Anja E. Hauser, Raluca A. Niesner
Format: Article
Language:English
Published: Nature Publishing Group 2017-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01538-9
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spelling doaj-5461e2efd91248698ccbbea37bccb7fc2021-05-11T07:53:59ZengNature Publishing GroupNature Communications2041-17232017-12-018111510.1038/s41467-017-01538-9Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculatureDavid Reismann0Jonathan Stefanowski1Robert Günther2Asylkhan Rakhymzhan3Romano Matthys4Reto Nützi5Sandra Zehentmeier6Katharina Schmidt-Bleek7Georg Petkau8Hyun-Dong Chang9Sandra Naundorf10York Winter11Fritz Melchers12Georg Duda13Anja E. Hauser14Raluca A. Niesner15Deutsches Rheuma-Forschungszentrum, A Leibniz Institute, Charitéplatz 1Deutsches Rheuma-Forschungszentrum, A Leibniz Institute, Charitéplatz 1Deutsches Rheuma-Forschungszentrum, A Leibniz Institute, Charitéplatz 1Deutsches Rheuma-Forschungszentrum, A Leibniz Institute, Charitéplatz 1RISystem AG, Talstraße 2ARISystem AG, Talstraße 2ADeutsches Rheuma-Forschungszentrum, A Leibniz Institute, Charitéplatz 1Julius Wolff Institute, Charité—Universitätsmedizin, Augustenburger Platz 1Deutsches Rheuma-Forschungszentrum, A Leibniz Institute, Charitéplatz 1Deutsches Rheuma-Forschungszentrum, A Leibniz Institute, Charitéplatz 1Deutsches Rheuma-Forschungszentrum, A Leibniz Institute, Charitéplatz 1Humboldt-Universität zu Berlin, Unter den Linden 6Deutsches Rheuma-Forschungszentrum, A Leibniz Institute, Charitéplatz 1Julius Wolff Institute, Charité—Universitätsmedizin, Augustenburger Platz 1Deutsches Rheuma-Forschungszentrum, A Leibniz Institute, Charitéplatz 1Deutsches Rheuma-Forschungszentrum, A Leibniz Institute, Charitéplatz 1Longitudinal imaging of bone marrow would shed insight into long-term cellular dynamics within this compartment. Here, the authors develop a multi-photon imaging approach for the mouse femur and reveal extensive vascular plasticity within the bone marrow during bone healing and steady-state homeostasis.https://doi.org/10.1038/s41467-017-01538-9
collection DOAJ
language English
format Article
sources DOAJ
author David Reismann
Jonathan Stefanowski
Robert Günther
Asylkhan Rakhymzhan
Romano Matthys
Reto Nützi
Sandra Zehentmeier
Katharina Schmidt-Bleek
Georg Petkau
Hyun-Dong Chang
Sandra Naundorf
York Winter
Fritz Melchers
Georg Duda
Anja E. Hauser
Raluca A. Niesner
spellingShingle David Reismann
Jonathan Stefanowski
Robert Günther
Asylkhan Rakhymzhan
Romano Matthys
Reto Nützi
Sandra Zehentmeier
Katharina Schmidt-Bleek
Georg Petkau
Hyun-Dong Chang
Sandra Naundorf
York Winter
Fritz Melchers
Georg Duda
Anja E. Hauser
Raluca A. Niesner
Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature
Nature Communications
author_facet David Reismann
Jonathan Stefanowski
Robert Günther
Asylkhan Rakhymzhan
Romano Matthys
Reto Nützi
Sandra Zehentmeier
Katharina Schmidt-Bleek
Georg Petkau
Hyun-Dong Chang
Sandra Naundorf
York Winter
Fritz Melchers
Georg Duda
Anja E. Hauser
Raluca A. Niesner
author_sort David Reismann
title Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature
title_short Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature
title_full Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature
title_fullStr Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature
title_full_unstemmed Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature
title_sort longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-12-01
description Longitudinal imaging of bone marrow would shed insight into long-term cellular dynamics within this compartment. Here, the authors develop a multi-photon imaging approach for the mouse femur and reveal extensive vascular plasticity within the bone marrow during bone healing and steady-state homeostasis.
url https://doi.org/10.1038/s41467-017-01538-9
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