Association of a novel endometrial cancer biomarker panel with prognostic risk, platinum insensitivity, and targetable therapeutic options.

Association of a novel endometrial cancer biomarker panel with prognostic risk, platinum insensitivity, and targetable therapeutic options.

During the past decade, the age-adjusted mortality rate for endometrial cancer (EC) increased 1.9% annually with TP53 mutant (TP53-mu) EC disproportionally represented in advanced disease and deaths. Therefore, we aimed to assess pivotal molecular parameters that differentiate clinical outcomes in h...

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Bibliographic Details
Main Authors:	Jesus Gonzalez Bosquet, Qing Zhang, William A Cliby, Jamie N Bakkum-Gamez, Ling Cen, Sean C Dowdy, Mark E Sherman, S John Weroha, Amy C Clayton, Benjamin R Kipp, Kevin C Halling, Fergus J Couch, Karl C Podratz
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2021-01-01
Series:	PLoS ONE
Online Access:	https://doi.org/10.1371/journal.pone.0245664

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