IL-4Rα-associated antigen processing by B cells promotes immunity in Nippostrongylus brasiliensis infection.

IL-4Rα-associated antigen processing by B cells promotes immunity in Nippostrongylus brasiliensis infection.

In this study, B cell function in protective T(H)2 immunity against N. brasiliensis infection was investigated. Protection against secondary infection depended on IL-4Rα and IL-13; but not IL-4. Protection did not associate with parasite specific antibody responses. Re-infection of B cell-specific I...

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Bibliographic Details
Main Authors:	William G C Horsnell, Matthew G Darby, Jennifer C Hoving, Natalie Nieuwenhuizen, Henry J McSorley, Hlumani Ndlovu, Saeeda Bobat, Matti Kimberg, Frank Kirstein, Anthony J Cutler, Benjamin Dewals, Adam F Cunningham, Frank Brombacher
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-10-01
Series:	PLoS Pathogens
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24204255/pdf/?tool=EBI

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