IL-4Rα-associated antigen processing by B cells promotes immunity in Nippostrongylus brasiliensis infection.
In this study, B cell function in protective T(H)2 immunity against N. brasiliensis infection was investigated. Protection against secondary infection depended on IL-4Rα and IL-13; but not IL-4. Protection did not associate with parasite specific antibody responses. Re-infection of B cell-specific I...
Main Authors: | William G C Horsnell, Matthew G Darby, Jennifer C Hoving, Natalie Nieuwenhuizen, Henry J McSorley, Hlumani Ndlovu, Saeeda Bobat, Matti Kimberg, Frank Kirstein, Anthony J Cutler, Benjamin Dewals, Adam F Cunningham, Frank Brombacher |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-10-01
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Series: | PLoS Pathogens |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24204255/pdf/?tool=EBI |
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