Allosteric Cannabinoid Receptor 1 (CB1) Ligands Reduce Ocular Pain and Inflammation

Allosteric Cannabinoid Receptor 1 (CB1) Ligands Reduce Ocular Pain and Inflammation

Cannabinoid receptor 1 (CB1) activation has been reported to reduce transient receptor potential cation channel subfamily V member 1 (TRPV1)-induced inflammatory responses and is anti-nociceptive and anti-inflammatory in corneal injury. We examined whether allosteric ligands, can modulate CB1 signal...

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Bibliographic Details
Main Authors: Dinesh Thapa, Elizabeth A. Cairns, Anna-Maria Szczesniak, Pushkar M. Kulkarni, Alex J. Straiker, Ganesh A. Thakur, Melanie E. M. Kelly
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
cannabinoids
allosteric ligands
cornea
pain
inflammation
Online Access:https://www.mdpi.com/1420-3049/25/2/417

Internet

https://www.mdpi.com/1420-3049/25/2/417

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