The role of apoptosis in autoantibody production

In normal conditions, the intracellular autoantigens reach the cell surface by apoptosis and are normally cleared by phagocytes without inflammation, nevertheless the lack of depuration of apoptotic material foster the autoantibody production in individuals genetically predisposed, equally defects i...

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Main Authors: E. López-Robles, D. Herrera-van-Oostdam, R. Herrera-Esparza, E. Avalos-Díaz
Format: Article
Language:English
Published: PAGEPress Publications 2011-09-01
Series:Reumatismo
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/316
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spelling doaj-54992b613ebc47e3b4e331f345db6ee22020-11-25T01:00:40ZengPAGEPress PublicationsReumatismo0048-74492240-26832011-09-01592879910.4081/reumatismo.2007.87The role of apoptosis in autoantibody productionE. López-RoblesD. Herrera-van-OostdamR. Herrera-EsparzaE. Avalos-DíazIn normal conditions, the intracellular autoantigens reach the cell surface by apoptosis and are normally cleared by phagocytes without inflammation, nevertheless the lack of depuration of apoptotic material foster the autoantibody production in individuals genetically predisposed, equally defects in signaling, execution and malfunction of the apoptotic pathways may induce autoimmunity, in consequence apoptosis is another way of understanding the autoimmunity (1)...http://www.reumatismo.org/index.php/reuma/article/view/316
collection DOAJ
language English
format Article
sources DOAJ
author E. López-Robles
D. Herrera-van-Oostdam
R. Herrera-Esparza
E. Avalos-Díaz
spellingShingle E. López-Robles
D. Herrera-van-Oostdam
R. Herrera-Esparza
E. Avalos-Díaz
The role of apoptosis in autoantibody production
Reumatismo
author_facet E. López-Robles
D. Herrera-van-Oostdam
R. Herrera-Esparza
E. Avalos-Díaz
author_sort E. López-Robles
title The role of apoptosis in autoantibody production
title_short The role of apoptosis in autoantibody production
title_full The role of apoptosis in autoantibody production
title_fullStr The role of apoptosis in autoantibody production
title_full_unstemmed The role of apoptosis in autoantibody production
title_sort role of apoptosis in autoantibody production
publisher PAGEPress Publications
series Reumatismo
issn 0048-7449
2240-2683
publishDate 2011-09-01
description In normal conditions, the intracellular autoantigens reach the cell surface by apoptosis and are normally cleared by phagocytes without inflammation, nevertheless the lack of depuration of apoptotic material foster the autoantibody production in individuals genetically predisposed, equally defects in signaling, execution and malfunction of the apoptotic pathways may induce autoimmunity, in consequence apoptosis is another way of understanding the autoimmunity (1)...
url http://www.reumatismo.org/index.php/reuma/article/view/316
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