Methods for Determining the Statistical Significance of Enrichment or Depletion of Gene Ontology Classifications under Weighted Membership
High-throughput molecular biology studies, such as microarray assays of gene expression, two-hybrid experiments for detecting protein interactions, or ChIP-Seq experiments for transcription factor binding, often result in an interesting set of genes—say, genes that are co-expressed or bound by the s...
Main Authors: | Ernesto eIacucci, Hans H. Zingg, Theodore J. Perkins |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-02-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00024/full |
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