Cell technologies in the treatment of rheumatic diseases
Rheumatic diseases are caused by chronic autoimmune processes that require long-term therapy, which leads to the formation of resistance to the drugs used. The search for new approaches to their treatment in recent years has been enriched with the use of cell therapy methods. They are considered in...
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Online Access: | https://rsp.mediar-press.net/rsp/article/view/2806 |
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doaj-54a4e39f974d44a684c9aaa36c39ac782021-08-02T09:05:53ZrusIMA-PRESS LLCНаучно-практическая ревматология1995-44841995-44922019-12-0157668569210.14412/1995-4484-2019-685-6922555Cell technologies in the treatment of rheumatic diseasesN. F. Soroka0M. P. Potapnev1N. A. Martusevich2Belarusian State Medical UniversityBelarusian State Medical University; Republican Research and Practical Center of Transfusiology and Medical BiotechnologiesBelarusian State Medical UniversityRheumatic diseases are caused by chronic autoimmune processes that require long-term therapy, which leads to the formation of resistance to the drugs used. The search for new approaches to their treatment in recent years has been enriched with the use of cell therapy methods. They are considered in this review of the literature and include the transplantation of hematopoietic stem cells, mesenchymal stem (stromal) cells, the induction or administration of T-regulatory cells, tolerogenic dendritic cells. The paper discusses methods of obtaining cell products, their safety and clinical use in patients with systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, and other rheumatic diseases, and treatment complications. Based on the analysis, the authors give the comparative characteristics of various types of tolerogenic cell therapy for rheumatic diseases and point out their advantages, disadvantages, and the specific features of clinical application.https://rsp.mediar-press.net/rsp/article/view/2806rheumatic diseasescell producttolerogenic cell therapy |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
N. F. Soroka M. P. Potapnev N. A. Martusevich |
spellingShingle |
N. F. Soroka M. P. Potapnev N. A. Martusevich Cell technologies in the treatment of rheumatic diseases Научно-практическая ревматология rheumatic diseases cell product tolerogenic cell therapy |
author_facet |
N. F. Soroka M. P. Potapnev N. A. Martusevich |
author_sort |
N. F. Soroka |
title |
Cell technologies in the treatment of rheumatic diseases |
title_short |
Cell technologies in the treatment of rheumatic diseases |
title_full |
Cell technologies in the treatment of rheumatic diseases |
title_fullStr |
Cell technologies in the treatment of rheumatic diseases |
title_full_unstemmed |
Cell technologies in the treatment of rheumatic diseases |
title_sort |
cell technologies in the treatment of rheumatic diseases |
publisher |
IMA-PRESS LLC |
series |
Научно-практическая ревматология |
issn |
1995-4484 1995-4492 |
publishDate |
2019-12-01 |
description |
Rheumatic diseases are caused by chronic autoimmune processes that require long-term therapy, which leads to the formation of resistance to the drugs used. The search for new approaches to their treatment in recent years has been enriched with the use of cell therapy methods. They are considered in this review of the literature and include the transplantation of hematopoietic stem cells, mesenchymal stem (stromal) cells, the induction or administration of T-regulatory cells, tolerogenic dendritic cells. The paper discusses methods of obtaining cell products, their safety and clinical use in patients with systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, and other rheumatic diseases, and treatment complications. Based on the analysis, the authors give the comparative characteristics of various types of tolerogenic cell therapy for rheumatic diseases and point out their advantages, disadvantages, and the specific features of clinical application. |
topic |
rheumatic diseases cell product tolerogenic cell therapy |
url |
https://rsp.mediar-press.net/rsp/article/view/2806 |
work_keys_str_mv |
AT nfsoroka celltechnologiesinthetreatmentofrheumaticdiseases AT mppotapnev celltechnologiesinthetreatmentofrheumaticdiseases AT namartusevich celltechnologiesinthetreatmentofrheumaticdiseases |
_version_ |
1721235627258675200 |