A Colorimetric Assay for the Detection of Glucose and H2O2 Based on Cu-Ag/g-C3N4/ZIF Hybrids with Superior Peroxidase Mimetic Activity

In this work, we report the synthesis of Cu-Ag bimetallic nanopartiles and g-C3N4 nanosheets decorated on zeolitic imidazolate framework-8 (ZIF-8) to form a Cu-Ag/g-C3N4/ZIF hybrid. The hybrid was synthesized...

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Main Authors:	Quan Pan, Yuelin Kong, Kuan Chen, Mi Mao, Xiaohui Wan, Xiaoyan She, Qingsong Gao, Yu He, Gongwu Song
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Series:	Molecules
Subjects:	Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF hybrid nanozyme colorimetric detection H<sub>2</sub>O<sub>2</sub> glucose
Online Access:	https://www.mdpi.com/1420-3049/25/19/4432

id	doaj-54cb27e1de78464c8cdeddd2e983244d
record_format	Article
spelling	doaj-54cb27e1de78464c8cdeddd2e983244d2020-11-25T03:33:31ZengMDPI AGMolecules1420-30492020-09-01254432443210.3390/molecules25194432A Colorimetric Assay for the Detection of Glucose and H<sub>2</sub>O<sub>2</sub> Based on Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF Hybrids with Superior Peroxidase Mimetic ActivityQuan Pan0Yuelin Kong1Kuan Chen2Mi Mao3Xiaohui Wan4Xiaoyan She5Qingsong Gao6Yu He7Gongwu Song8Hubei Province Fiber Inspection Bureau, Wuhan 430061, ChinaHubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, ChinaHubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, ChinaHubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, ChinaHubei Province Fiber Inspection Bureau, Wuhan 430061, ChinaHubei Province Fiber Inspection Bureau, Wuhan 430061, ChinaHubei Province Fiber Inspection Bureau, Wuhan 430061, ChinaHubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, ChinaHubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, ChinaIn this work, we report the synthesis of Cu-Ag bimetallic nanopartiles and g-C<sub>3</sub>N<sub>4</sub> nanosheets decorated on zeolitic imidazolate framework-8 (ZIF-8) to form a Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF hybrid. The hybrid was synthesized and characterized by Transmission electron microscopy (TEM), Fourier transformed infrared (FTIR), the X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF hybrid has intrinsic peroxidaselike catalytic activity towards the oxidation of TMB in the presence of H<sub>2</sub>O<sub>2</sub>. The situ synthesis of Cu-Ag bimetallic nanopartiles on 2D support such as g-C<sub>3</sub>N<sub>4</sub> nanosheets would significantly enhance the peroxidaselike catalytic properties of individual Cu-Ag bimetallic nanopartiles and the g-C<sub>3</sub>N<sub>4</sub> nanosheets. After loading of Cu-Ag bimetallic nanopartiles and g-C<sub>3</sub>N<sub>4</sub> nanosheets on the ZIF-8, the hybrids exhibited superior peroxidaselike catalytic activity and good recyclability. Then, this method was applied for detecting glucose in human serum, owing the significant potential for detection of metabolites with H<sub>2</sub>O<sub>2</sub>-generation reactions.https://www.mdpi.com/1420-3049/25/19/4432Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF hybridnanozymecolorimetric detectionH<sub>2</sub>O<sub>2</sub>glucose
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Quan Pan Yuelin Kong Kuan Chen Mi Mao Xiaohui Wan Xiaoyan She Qingsong Gao Yu He Gongwu Song
spellingShingle	Quan Pan Yuelin Kong Kuan Chen Mi Mao Xiaohui Wan Xiaoyan She Qingsong Gao Yu He Gongwu Song A Colorimetric Assay for the Detection of Glucose and H<sub>2</sub>O<sub>2</sub> Based on Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF Hybrids with Superior Peroxidase Mimetic Activity Molecules Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF hybrid nanozyme colorimetric detection H<sub>2</sub>O<sub>2</sub> glucose
author_facet	Quan Pan Yuelin Kong Kuan Chen Mi Mao Xiaohui Wan Xiaoyan She Qingsong Gao Yu He Gongwu Song
author_sort	Quan Pan
title	A Colorimetric Assay for the Detection of Glucose and H<sub>2</sub>O<sub>2</sub> Based on Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF Hybrids with Superior Peroxidase Mimetic Activity
title_short	A Colorimetric Assay for the Detection of Glucose and H<sub>2</sub>O<sub>2</sub> Based on Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF Hybrids with Superior Peroxidase Mimetic Activity
title_full	A Colorimetric Assay for the Detection of Glucose and H<sub>2</sub>O<sub>2</sub> Based on Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF Hybrids with Superior Peroxidase Mimetic Activity
title_fullStr	A Colorimetric Assay for the Detection of Glucose and H<sub>2</sub>O<sub>2</sub> Based on Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF Hybrids with Superior Peroxidase Mimetic Activity
title_full_unstemmed	A Colorimetric Assay for the Detection of Glucose and H<sub>2</sub>O<sub>2</sub> Based on Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF Hybrids with Superior Peroxidase Mimetic Activity
title_sort	colorimetric assay for the detection of glucose and h<sub>2</sub>o<sub>2</sub> based on cu-ag/g-c<sub>3</sub>n<sub>4</sub>/zif hybrids with superior peroxidase mimetic activity
publisher	MDPI AG
series	Molecules
issn	1420-3049
publishDate	2020-09-01
description	In this work, we report the synthesis of Cu-Ag bimetallic nanopartiles and g-C<sub>3</sub>N<sub>4</sub> nanosheets decorated on zeolitic imidazolate framework-8 (ZIF-8) to form a Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF hybrid. The hybrid was synthesized and characterized by Transmission electron microscopy (TEM), Fourier transformed infrared (FTIR), the X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF hybrid has intrinsic peroxidaselike catalytic activity towards the oxidation of TMB in the presence of H<sub>2</sub>O<sub>2</sub>. The situ synthesis of Cu-Ag bimetallic nanopartiles on 2D support such as g-C<sub>3</sub>N<sub>4</sub> nanosheets would significantly enhance the peroxidaselike catalytic properties of individual Cu-Ag bimetallic nanopartiles and the g-C<sub>3</sub>N<sub>4</sub> nanosheets. After loading of Cu-Ag bimetallic nanopartiles and g-C<sub>3</sub>N<sub>4</sub> nanosheets on the ZIF-8, the hybrids exhibited superior peroxidaselike catalytic activity and good recyclability. Then, this method was applied for detecting glucose in human serum, owing the significant potential for detection of metabolites with H<sub>2</sub>O<sub>2</sub>-generation reactions.
topic	Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF hybrid nanozyme colorimetric detection H<sub>2</sub>O<sub>2</sub> glucose
url	https://www.mdpi.com/1420-3049/25/19/4432
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A Colorimetric Assay for the Detection of Glucose and H<sub>2</sub>O<sub>2</sub> Based on Cu-Ag/g-C<sub>3</sub>N<sub>4</sub>/ZIF Hybrids with Superior Peroxidase Mimetic Activity

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