Screening of Dietary Ingredients against the Honey Bee Parasite <i>Nosema ceranae</i>
<i>Nosema ceranae</i> is a major pathogen in the beekeeping sector, responsible for nosemosis. This disease is hard to manage since its symptomatology is masked until a strong collapse of the colony population occurs. Conversely, no medicaments are available in the market to counteract n...
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doaj-54cfb22a6f02488fb91f5b279ad703492021-09-26T00:54:16ZengMDPI AGPathogens2076-08172021-09-01101117111710.3390/pathogens10091117Screening of Dietary Ingredients against the Honey Bee Parasite <i>Nosema ceranae</i>Chiara Braglia0Daniele Alberoni1Martin Pablo Porrini2Paula Melisa Garrido3Loredana Baffoni4Diana Di Gioia5Department of Agricultural and Food Sciences (DISTAL), University of Bologna, Viale Fanin 44, 40127 Bologna, ItalyDepartment of Agricultural and Food Sciences (DISTAL), University of Bologna, Viale Fanin 44, 40127 Bologna, ItalyInstituto de Investigaciones en Producción Sanidad y Ambiente (IIPROSAM), Centro Científico Tecnológico Mar del Plata-CONICET-UNMdP-CIC-PBA, Funes 3350, Mar del Plata Zc 7600, ArgentinaInstituto de Investigaciones en Producción Sanidad y Ambiente (IIPROSAM), Centro Científico Tecnológico Mar del Plata-CONICET-UNMdP-CIC-PBA, Funes 3350, Mar del Plata Zc 7600, ArgentinaDepartment of Agricultural and Food Sciences (DISTAL), University of Bologna, Viale Fanin 44, 40127 Bologna, ItalyDepartment of Agricultural and Food Sciences (DISTAL), University of Bologna, Viale Fanin 44, 40127 Bologna, Italy<i>Nosema ceranae</i> is a major pathogen in the beekeeping sector, responsible for nosemosis. This disease is hard to manage since its symptomatology is masked until a strong collapse of the colony population occurs. Conversely, no medicaments are available in the market to counteract nosemosis, and only a few feed additives, with claimed antifungal action, are available. New solutions are strongly required, especially based on natural methods alternative to veterinary drugs that might develop resistance or strongly pollute honey bees and the environment. This study aims at investigating the nosemosis antiparasitic potential of some plant extracts, microbial fermentation products, organic acids, food chain waste products, bacteriocins, and fungi. Honey bees were singularly infected with 5 × 10<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mrow></mrow><mn>4</mn></msup></semantics></math></inline-formula> freshly prepared <i>N. ceranae</i> spores, reared in cages and fed ad libitum with sugar syrup solution containing the active ingredient. <i>N. ceranae</i> in the gut of honey bees was estimated using qPCR. The results showed that some of the ingredients administered, such as acetic acid at high concentration, p-coumaric acid, and <i>Saccharomyces</i> sp. strain KIA1, were effective in the control of nosemosis. On the other hand, wine acetic acid strongly increased the <i>N. ceranae</i> amount. This study investigates the possibility of using compounds such as organic acids or biological agents including those at the base of the circular economy, i.e., wine waste production, in order to improve honeybee health.https://www.mdpi.com/2076-0817/10/9/1117nosemosis<i>Vairimorpha ceranae</i>nisin<i>Saccharomyces</i> sp.acetic acidpara-coumaric acid |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chiara Braglia Daniele Alberoni Martin Pablo Porrini Paula Melisa Garrido Loredana Baffoni Diana Di Gioia |
spellingShingle |
Chiara Braglia Daniele Alberoni Martin Pablo Porrini Paula Melisa Garrido Loredana Baffoni Diana Di Gioia Screening of Dietary Ingredients against the Honey Bee Parasite <i>Nosema ceranae</i> Pathogens nosemosis <i>Vairimorpha ceranae</i> nisin <i>Saccharomyces</i> sp. acetic acid para-coumaric acid |
author_facet |
Chiara Braglia Daniele Alberoni Martin Pablo Porrini Paula Melisa Garrido Loredana Baffoni Diana Di Gioia |
author_sort |
Chiara Braglia |
title |
Screening of Dietary Ingredients against the Honey Bee Parasite <i>Nosema ceranae</i> |
title_short |
Screening of Dietary Ingredients against the Honey Bee Parasite <i>Nosema ceranae</i> |
title_full |
Screening of Dietary Ingredients against the Honey Bee Parasite <i>Nosema ceranae</i> |
title_fullStr |
Screening of Dietary Ingredients against the Honey Bee Parasite <i>Nosema ceranae</i> |
title_full_unstemmed |
Screening of Dietary Ingredients against the Honey Bee Parasite <i>Nosema ceranae</i> |
title_sort |
screening of dietary ingredients against the honey bee parasite <i>nosema ceranae</i> |
publisher |
MDPI AG |
series |
Pathogens |
issn |
2076-0817 |
publishDate |
2021-09-01 |
description |
<i>Nosema ceranae</i> is a major pathogen in the beekeeping sector, responsible for nosemosis. This disease is hard to manage since its symptomatology is masked until a strong collapse of the colony population occurs. Conversely, no medicaments are available in the market to counteract nosemosis, and only a few feed additives, with claimed antifungal action, are available. New solutions are strongly required, especially based on natural methods alternative to veterinary drugs that might develop resistance or strongly pollute honey bees and the environment. This study aims at investigating the nosemosis antiparasitic potential of some plant extracts, microbial fermentation products, organic acids, food chain waste products, bacteriocins, and fungi. Honey bees were singularly infected with 5 × 10<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mrow></mrow><mn>4</mn></msup></semantics></math></inline-formula> freshly prepared <i>N. ceranae</i> spores, reared in cages and fed ad libitum with sugar syrup solution containing the active ingredient. <i>N. ceranae</i> in the gut of honey bees was estimated using qPCR. The results showed that some of the ingredients administered, such as acetic acid at high concentration, p-coumaric acid, and <i>Saccharomyces</i> sp. strain KIA1, were effective in the control of nosemosis. On the other hand, wine acetic acid strongly increased the <i>N. ceranae</i> amount. This study investigates the possibility of using compounds such as organic acids or biological agents including those at the base of the circular economy, i.e., wine waste production, in order to improve honeybee health. |
topic |
nosemosis <i>Vairimorpha ceranae</i> nisin <i>Saccharomyces</i> sp. acetic acid para-coumaric acid |
url |
https://www.mdpi.com/2076-0817/10/9/1117 |
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