Negative drift of sedation depth in critically ill patients receiving constant minimum alveolar concentration of isoflurane, sevoflurane, or desflurane: a randomized controlled trial

Negative drift of sedation depth in critically ill patients receiving constant minimum alveolar concentration of isoflurane, sevoflurane, or desflurane: a randomized controlled trial

Abstract Background Intensive care unit (ICU) physicians have extended the minimum alveolar concentration (MAC) to deliver and monitor long-term volatile sedation in critically ill patients. There is limited evidence of MAC’s reliability in controlling sedation depth in this setting. We hypothesized...

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Bibliographic Details
Main Authors: Adrian-Iustin Georgevici, Theodoros Kyprianou, Jennifer Herzog-Niescery, Livia Procopiuc, Sivakkanan Loganathan, Thomas Peter Weber, Martin Bellgardt
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Critical Care
Subjects:
Critical care
Desflurane
Electroencephalography
Inhalational sedation
Isoflurane
Narcotrend
Online Access:https://doi.org/10.1186/s13054-021-03556-y

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