What Is the Evidence that Parkinson’s Disease Is a Prion Disorder, Which Originates in the Gut?

What Is the Evidence that Parkinson’s Disease Is a Prion Disorder, Which Originates in the Gut?

Parkinson’s disease (PD) is a neurodegenerative disorder resulting from degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). PD is characterized by motor dysfunctions as well as gastrointestinal symptoms and mental impairment. The pathological hallmark of PD is an accum...

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Bibliographic Details
Main Authors: Małgorzata Kujawska, Jadwiga Jodynis-Liebert
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
enteric nervous system
dysbiosis
Braak’s staging system
Online Access:https://www.mdpi.com/1422-0067/19/11/3573

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