Coiled-Coil Antagonism Regulates Activity of Venus Flytrap-Domain-Containing Sensor Kinases of the BvgS Family
Bordetella pertussis controls the expression of its virulence regulon through the two-component system BvgAS. BvgS is a prototype for a family of multidomain sensor kinases. In BvgS, helical linkers connect periplasmic Venus flytrap (VFT) perception domains to a cytoplasmic Per-Arnt-Sim (PAS) domain...
Main Authors: | Elodie Lesne, Elian Dupré, Marc F. Lensink, Camille Locht, Rudy Antoine, Francoise Jacob-Dubuisson, Scott J. Hultgren |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2018-02-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/9/1/e02052-17 |
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