The deleterious effect of cholesterol and protection by quercetin on mitochondrial bioenergetics of pancreatic β-cells, glycemic control and inflammation: In vitro and in vivo studies
Studying rats fed high cholesterol diet and a pancreatic β-cell line (Min6), we aimed to determine the mechanisms by which quercetin protects against cholesterol-induced pancreatic β-cell dysfunction and impairments in glycemic control. Quercetin prevented the increase in total plasma cholesterol, b...
Main Authors: | Catalina Carrasco-Pozo, Kah Ni Tan, Marjorie Reyes-Farias, Nicole De La Jara, Shyuan Thieu Ngo, Diego Fernando Garcia-Diaz, Paola Llanos, Maria Jose Cires, Karin Borges |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-10-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231716301215 |
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