Endoplasmic Reticulum Stress Cooperates in Silica Nanoparticles-Induced Macrophage Apoptosis via Activation of CHOP-Mediated Apoptotic Signaling Pathway

Endoplasmic Reticulum Stress Cooperates in Silica Nanoparticles-Induced Macrophage Apoptosis via Activation of CHOP-Mediated Apoptotic Signaling Pathway

While silica nanoparticles (SiNPs) have wide applications, they inevitably increase atmospheric particulate matter and human exposure to this nanomaterial. Numerous studies have focused on how to disclose SiNP toxicity and on understanding its toxic mechanisms. However, there are few studies in the...

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Bibliographic Details
Main Authors: Fenglei Chen, Jiaqi Jin, Jiahui Hu, Yujing Wang, Zhiyu Ma, Jinlong Zhang
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
silica nanoparticles
endoplasmic reticulum stress
apoptosis
chop
Online Access:https://www.mdpi.com/1422-0067/20/23/5846

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