Identification of HLA-DRB1 association to adalimumab immunogenicity.
Anti-drug antibody formation occurs with most biological agents across disease states, but the mechanism by which they are formed is unknown. The formation of anti-drug antibodies to adalimumab (AAA) may decrease its therapeutic effects in some patients. HLA alleles have been reported to be associat...
Main Authors: | Mohan Liu, Jacob Degner, Justin Wade Davis, Kenneth B Idler, Ahmed Nader, Nael M Mostafa, Jeffrey F Waring |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5882140?pdf=render |
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