Association between sleep duration and electrocardiographic ischemic changes in middle-aged population: Isfahan Healthy Heart Program

• Main Authors: Mahdi Khani, Jamshid Najafian, Marzieh Taheri, Afshan Akhavan-Tabib, Shidokht Hosseini
• Format: Article
• Language: English
• Published: Vesnu Publications 2018-06-01
• Series: ARYA Atherosclerosis
• Subjects: Myocardial Ischemia; Electrocardiography; Sleep Deprivation
• Online Access: http://arya.mui.ac.ir/index.php/arya/article/view/1656
• ISSN: 1735-3955; 2251-6638

<div><p><strong>BACKGROUND:</strong> Recent studies examining the association between sleep duration and cardiovascular disease (CVD) showed inconsistent results. The aim of our study was to evaluate the association between self-reported night sleep duration and ischemic changes in electrocardiography (ECG).</p><p><strong>METHODS:</strong> We conducted this cross-sectional study on 3513 participants from Iranian middle-aged population as a part of Isfahan Healthy Heart Program (IHHP), Isfahan, Iran. Sleep duration was obtained by questioning participants. The frequency of electrocardiographic ischemic changes was calculated using ECG Minnesota coding system.</p><p><strong>RESULTS:</strong><strong> </strong>Short sleep duration was associated with increased frequency of electrocardiographic ischemic changes. In a fully adjusted multiple logistic regression analysis, the odds ratio (OR) for short sleep duration less than 5 hours per night was 1.501 [95% confidence interval (CI) for OR: 1.085-2.076] compared to 8 hours of sleep. After stratifying the study population into sex groups, the association remained significant only in women. The OR for short sleep less than <br /> 5 hours per night was 1.565 (95% CI for OR: 1.052-2.329) and 1.455 (95% CI for OR: 0.833-2.539) in women and men, respectively. There was no association between long sleep duration and electrocardiographic ischemic changes in men and women.</p><p><strong>CONCLUSION:</strong> We concluded that there is a positive association between short sleep duration and frequency of electrocardiographic ischemic changes in middle-aged women. This association suggests that short sleep duration may increase the risk of ischemic heart disease (IHD) in women, and this need to be evaluated in further studies.</p></div>