The “inherent vice” in the anti-angiogenic theory may cause the highly metastatic cancer to spread more aggressively
Abstract Although anti-angiogenic (AA) therapy is widely used in clinical practice, it is often challenged by insufficient efficacy and intrinsic resistance. Some studies have reported that AA therapy can even increase tumor metastasis. However, whether this is due to a specific AA drug causing a sp...
Main Authors: | Denian Wang, Chun Tan, Fei Xiao, Lan Zou, Lijun Wang, Yong’gang Wei, Hanshuo Yang, Wei Zhang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-02534-1 |
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