The Bilateral Ovariectomy in a Female Animal Exacerbates the Pathogenesis of an Intracranial Aneurysm

The Bilateral Ovariectomy in a Female Animal Exacerbates the Pathogenesis of an Intracranial Aneurysm

Considering the poor outcome of subarachnoid hemorrhage (SAH) due to the rupture of intracranial aneurysms (IA), mechanisms underlying the pathogenesis of IAs, especially the rupture of lesions, should be clarified. In the present study, a rat model of IAs in which induced lesions spontaneously rupt...

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Bibliographic Details
Main Authors: Mieko Oka, Isao Ono, Kampei Shimizu, Mika Kushamae, Haruka Miyata, Takakazu Kawamata, Tomohiro Aoki
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Brain Sciences
Subjects:
intracranial aneurysm
subarachnoid hemorrhage
estrogen
female
endothelial cell
macrophage
Online Access:https://www.mdpi.com/2076-3425/10/6/335

Internet

https://www.mdpi.com/2076-3425/10/6/335

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