Acetyl-L-carnitine improves behavior and dendritic morphology in a mouse model of Rett syndrome.
Rett syndrome (RTT) is a devastating neurodevelopmental disorder affecting 1 in 10,000 girls. Approximately 90% of cases are caused by spontaneous mutations in the X-linked gene encoding methyl-CpG-binding protein 2 (MeCP2). Girls with RTT suffer from severe motor, respiratory, cognitive and social...
Main Authors: | Laura R Schaevitz, Raffaella Nicolai, Carla M Lopez, Stefania D'Iddio, Emerenziana Iannoni, Joanne E Berger-Sweeney |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3515484?pdf=render |
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