Radiation-Induced DNMT3B Promotes Radioresistance in Nasopharyngeal Carcinoma through Methylation of p53 and p21
Radiotherapy with or without concurrent chemotherapy is the standard treatment for nasopharyngeal carcinoma (NPC) patients, whose efficacy is limited partly by intrinsic and acquired radioresistance. DNA methyltransferase 3B (DNMT3B) has been reported to participate in tumorigenesis via DNA methylat...
Main Authors: | Cheng Wu, Ergang Guo, Jun Ming, Wei Sun, Xin Nie, Lu Sun, Shan Peng, Min Luo, Dongbo Liu, Linli Zhang, Qi Mei, Guoxian Long, Guangyuan Hu, Guoqing Hu |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-06-01
|
Series: | Molecular Therapy: Oncolytics |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2372770520300577 |
Similar Items
-
SALL4 induces radioresistance in nasopharyngeal carcinoma via the ATM/Chk2/p53 pathway
by: Xin Nie, et al.
Published: (2019-04-01) -
Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr
by: Fedrigo Carlos A, et al.
Published: (2011-11-01) -
LMP1‐positive extracellular vesicles promote radioresistance in nasopharyngeal carcinoma cells through P38 MAPK signaling
by: Zhibao Zhang, et al.
Published: (2019-10-01) -
Baicalin reverses radioresistance in nasopharyngeal carcinoma by downregulating autophagy
by: Cong Wang, et al.
Published: (2020-01-01) -
miR-181a Upregulation Promotes Radioresistance of Nasopharyngeal Carcinoma by Targeting RKIP
by: Huang W, et al.
Published: (2019-12-01)