Heart disease in patients with haemoglobinopathies

Hereditary hemoglobin disorders, also termed haemoglobinopathies, include mainly beta -thalasszemia and sickle cell disease and represent the most common monogenic disorders in human. Cardiac complications are still a leading cause of mortality and morbidity in patients with haemoglobinopathy, altho...

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Bibliographic Details
Main Authors: Dimitrios Farmakis, George Papingiotis
Format: Article
Language:English
Published: PAGEPress Publications 2018-04-01
Series:Thalassemia Reports
Subjects:
Online Access:https://www.pagepressjournals.org/index.php/thal/article/view/7480
Description
Summary:Hereditary hemoglobin disorders, also termed haemoglobinopathies, include mainly beta -thalasszemia and sickle cell disease and represent the most common monogenic disorders in human. Cardiac complications are still a leading cause of mortality and morbidity in patients with haemoglobinopathy, although heart disease due to either severe anaemia or iron overload have dramatically reduced in patient populations receiving modern regular therapy and follow-up. The spectrum of cardiovascular manifestations in haemoglobinopathies is wide and includes ventricular dysfunction, pulmonary hypertension, pericarditis-myocarditis, arrhythmias stroke and thromboembolic events...
ISSN:2039-4357
2039-4365