Targeted Derivation of Organotypic Glucose- and GLP-1-Responsive β Cells Prior to Transplantation into Diabetic Recipients

Targeted Derivation of Organotypic Glucose- and GLP-1-Responsive β Cells Prior to Transplantation into Diabetic Recipients

Summary: Generation of functional β cells from pluripotent sources would accelerate diagnostic and therapeutic applications for diabetes research and therapy. However, it has been challenging to generate competent β cells with dynamic insulin-secretory capacity to glucose and incretin stimulations....

Full description

Bibliographic Details
Main Authors: Yaxi Zhu, Jason M. Tonne, Qian Liu, Claire A. Schreiber, Zhiguang Zhou, Kuntol Rakshit, Aleksey V. Matveyenko, Andre Terzic, Dennis Wigle, Yogish C. Kudva, Yasuhiro Ikeda
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119302589

Similar Items

Similar Items