Epigenome-Wide DNA Methylation Profiling Identifies Differential Methylation Biomarkers in High-Grade Bladder Cancer
Epigenetic changes, including CpG island hypermethylation, occur frequently in bladder cancer (BC) and may be exploited for BC detection and distinction between high-grade (HG) and low-grade (LG) disease. Genome-wide methylation analysis was performed using Agilent Human CpG Island Microarrays to de...
Main Authors: | Ekaterina Olkhov-Mitsel, Andrea J. Savio, Ken J. Kron, Vaijayanti V. Pethe, Thomas Hermanns, Neil E. Fleshner, Bas W. van Rhijn, Theodorus H. van der Kwast, Alexandre R. Zlotta, Bharati Bapat |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2017-04-01
|
Series: | Translational Oncology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1936523316302583 |
Similar Items
-
Exploring targets of TET2-mediated methylation reprogramming as potential discriminators of prostate cancer progression
by: Shivani Kamdar, et al.
Published: (2019-03-01) -
Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays.
by: Ken Kron, et al.
Published: (2009-01-01) -
Total Knock-Down of the Cancer Epigenome by Methylation Subtraction
by: Pei-chi Hou, et al.
Published: (2010) -
The role of DNA methylation in directing the functional organization of the cancer epigenome
by: Lay, Fides D., et al.
Published: (2015) -
A urine-based DNA methylation assay, ProCUrE, to identify clinically significant prostate cancer
by: Fang Zhao, et al.
Published: (2018-11-01)