Power estimations for non-primary outcomes in randomised clinical trials

Objective and methods: It is rare that trialists report power estimations of non-primary outcomes. In the present article, we will describe how to define a valid hierarchy of outcomes in a randomised clinical trial, to limit problems with Type I and Type II errors, using considerations on the clinic...

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Bibliographic Details
Main Authors: Per Winkel, Janus Christian Jakobsen, Jørgen Hilden, Christian Gluud, Jørn Wetterslev, Christian Ovesen
Format: Article
Published: BMJ Publishing Group 2019-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/9/6/e027092.full

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