<b>Protein restriction during intrauterine and lactation periods: effects on testicular development in pre-puberty rats
Current study investigates the effects of maternal protein restriction during pregnancy and lactation on the testis of immature rats. Female Wistar rats were mated and, after confirming pregnancy, they were divided into two groups: undernourished group (UG) fed on a diet with casein 8%, and control...
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Universidade Estadual de Maringá
2015-03-01
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doaj-559f29b836cb478995246c8b5ff0db812020-11-25T02:57:34ZengUniversidade Estadual de MaringáActa Scientiarum : Biological Sciences1679-92831807-863X2015-03-0137110711210.4025/actascibiolsci.v37i1.2192911737<b>Protein restriction during intrauterine and lactation periods: effects on testicular development in pre-puberty ratsJessica Santana de Oliveira0Alluanan Adelson do Nascimento Silva1Carolina Peixoto Magalhães2Sandra Lopes de Souza3Valdemiro Amaro da Silva Junior4Elizabeth Neves de Melo5Universidade Federal Rural de PernambucoUniversidade Federal Rural de PernambucoUniversidade Federal de PernambucoUniversidade Federal de PernambucoUniversidade Federal Rural de PernambucoUniversidade Federal de PernambucoCurrent study investigates the effects of maternal protein restriction during pregnancy and lactation on the testis of immature rats. Female Wistar rats were mated and, after confirming pregnancy, they were divided into two groups: undernourished group (UG) fed on a diet with casein 8%, and control group (CG) fed on a diet with casein 17 %, during pregnancy and lactation. After weaning, male offspring from the two experimental groups were fed on normal diet up to 35 days old when they were euthanized. Body and testicular weights decreased in UG when compared to those in CG. Volumetric density of seminiferous tubules was higher in CG whilst intertubular space increased in UG. The number of lumenated seminiferous tubules was higher in CG than in UG. Tubular diameter, seminiferous epithelium height and total length of seminiferous tubules were lower in UG. Round spermatids were frequently found in seminiferous tubules cross-section of CG. On the other hand, spermatocytes I in prophases was the germ cell commonly found in seminiferous tubules cross-sections of UG. Undernutrition during pregnancy and lactation period of the male Wistar rats altered the morphometric testicular parameters related to tubular compartment and delayed the onset of spermatogenesis.http://186.233.154.254/ojs/index.php/ActaSciBiolSci/article/view/21929testesseminiferous tubulesmorphometryundernutrition |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jessica Santana de Oliveira Alluanan Adelson do Nascimento Silva Carolina Peixoto Magalhães Sandra Lopes de Souza Valdemiro Amaro da Silva Junior Elizabeth Neves de Melo |
spellingShingle |
Jessica Santana de Oliveira Alluanan Adelson do Nascimento Silva Carolina Peixoto Magalhães Sandra Lopes de Souza Valdemiro Amaro da Silva Junior Elizabeth Neves de Melo <b>Protein restriction during intrauterine and lactation periods: effects on testicular development in pre-puberty rats Acta Scientiarum : Biological Sciences testes seminiferous tubules morphometry undernutrition |
author_facet |
Jessica Santana de Oliveira Alluanan Adelson do Nascimento Silva Carolina Peixoto Magalhães Sandra Lopes de Souza Valdemiro Amaro da Silva Junior Elizabeth Neves de Melo |
author_sort |
Jessica Santana de Oliveira |
title |
<b>Protein restriction during intrauterine and lactation periods: effects on testicular development in pre-puberty rats |
title_short |
<b>Protein restriction during intrauterine and lactation periods: effects on testicular development in pre-puberty rats |
title_full |
<b>Protein restriction during intrauterine and lactation periods: effects on testicular development in pre-puberty rats |
title_fullStr |
<b>Protein restriction during intrauterine and lactation periods: effects on testicular development in pre-puberty rats |
title_full_unstemmed |
<b>Protein restriction during intrauterine and lactation periods: effects on testicular development in pre-puberty rats |
title_sort |
<b>protein restriction during intrauterine and lactation periods: effects on testicular development in pre-puberty rats |
publisher |
Universidade Estadual de Maringá |
series |
Acta Scientiarum : Biological Sciences |
issn |
1679-9283 1807-863X |
publishDate |
2015-03-01 |
description |
Current study investigates the effects of maternal protein restriction during pregnancy and lactation on the testis of immature rats. Female Wistar rats were mated and, after confirming pregnancy, they were divided into two groups: undernourished group (UG) fed on a diet with casein 8%, and control group (CG) fed on a diet with casein 17 %, during pregnancy and lactation. After weaning, male offspring from the two experimental groups were fed on normal diet up to 35 days old when they were euthanized. Body and testicular weights decreased in UG when compared to those in CG. Volumetric density of seminiferous tubules was higher in CG whilst intertubular space increased in UG. The number of lumenated seminiferous tubules was higher in CG than in UG. Tubular diameter, seminiferous epithelium height and total length of seminiferous tubules were lower in UG. Round spermatids were frequently found in seminiferous tubules cross-section of CG. On the other hand, spermatocytes I in prophases was the germ cell commonly found in seminiferous tubules cross-sections of UG. Undernutrition during pregnancy and lactation period of the male Wistar rats altered the morphometric testicular parameters related to tubular compartment and delayed the onset of spermatogenesis. |
topic |
testes seminiferous tubules morphometry undernutrition |
url |
http://186.233.154.254/ojs/index.php/ActaSciBiolSci/article/view/21929 |
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