Research Advances in the Correlation between Peroxisome Proliferator-Activated Receptor-γ and Digestive Cancers

Peroxisome proliferator-activated receptor-γ (PPARγ) is a class of ligand-activated nuclear transcription factors, which is a member of type II nuclear receptor superfamily. Previous studies demonstrate that PPARγ is expressed in a variety of tumor tissues and is closely associated with the prolifer...

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Bibliographic Details
Main Authors: Shuqi Xu, Xuanfu Xu
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2018/5289859
Description
Summary:Peroxisome proliferator-activated receptor-γ (PPARγ) is a class of ligand-activated nuclear transcription factors, which is a member of type II nuclear receptor superfamily. Previous studies demonstrate that PPARγ is expressed in a variety of tumor tissues and is closely associated with the proliferation and prognosis of digestive system tumors by its roles in mediation of cell differentiation, induction of cell apoptosis, and inhibition of cell proliferation.
ISSN:1687-4757
1687-4765