Histopathological observation of immunized rhesus macaques with plague vaccines after subcutaneous infection of Yersinia pestis.

Histopathological observation of immunized rhesus macaques with plague vaccines after subcutaneous infection of Yersinia pestis.

In our previous study, complete protection was observed in Chinese-origin rhesus macaques immunized with SV1 (20 µg F1 and 10 µg rV270) and SV2 (200 µg F1 and 100 µg rV270) subunit vaccines and with EV76 live attenuated vaccine against subcutaneous challenge with 6×10(6) CFU of Y. pestis. In the pre...

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Main Authors: Guang Tian, Yefeng Qiu, Zhizhen Qi, Xiaohong Wu, Qingwen Zhang, Yujing Bi, Yonghai Yang, Yuchuan Li, Xiaoyan Yang, Youquan Xin, Cunxiang Li, Baizhong Cui, Zuyun Wang, Hu Wang, Ruifu Yang, Xiaoyi Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084797?pdf=render

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