A Novel Singular Value Decomposition-Based Denoising Method in 4-Dimensional Computed Tomography of the Brain in Stroke Patients with Statistical Evaluation
Computed tomography (CT) is a widely used medical imaging modality for diagnosing various diseases. Among CT techniques, 4-dimensional CT perfusion (4D-CTP) of the brain is established in most centers for diagnosing strokes and is considered the gold standard for hyperacute stroke diagnosis. However...
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doaj-560ad595674f456e8407aab1ce0c2cd92020-11-25T02:33:29ZengMDPI AGSensors1424-82202020-05-01203063306310.3390/s20113063A Novel Singular Value Decomposition-Based Denoising Method in 4-Dimensional Computed Tomography of the Brain in Stroke Patients with Statistical EvaluationWonseok Yang0Jun-Yong Hong1Jeong-Youn Kim2Seung-ho Paik3Seung Hyun Lee4Ji-Su Park5Gihyoun Lee6Beop Min Kim7Young-Jin Jung8Department of Radiology, Dong-A University Hospital, Busan 49201, KoreaDepartment of Multidisciplinary Radiological Science, Graduate School, Dongseo University, Busan 47011, KoreaClinical Emotion and Cognition Research Laboratory, Inje University Ilsan Paik Hospital, Goyang 10380, KoreaDepartment of Bioengineering, Korea University, Seoul 02841, KoreaDepartment of Bioengineering, Korea University, Seoul 02841, KoreaAdvanced Human Resource Development Project Group for Health Care in Aging Friendly Industry, Dongseo University, Busan 47011, KoreaDepartment of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 02841, KoreaDepartment of Bioengineering, Korea University, Seoul 02841, KoreaDepartment of Multidisciplinary Radiological Science, Graduate School, Dongseo University, Busan 47011, KoreaComputed tomography (CT) is a widely used medical imaging modality for diagnosing various diseases. Among CT techniques, 4-dimensional CT perfusion (4D-CTP) of the brain is established in most centers for diagnosing strokes and is considered the gold standard for hyperacute stroke diagnosis. However, because the detrimental effects of high radiation doses from 4D-CTP may cause serious health risks in stroke survivors, our research team aimed to introduce a novel image-processing technique. Our singular value decomposition (SVD)-based image-processing technique can improve image quality, first, by separating several image components using SVD and, second, by reconstructing signal component images to remove noise, thereby improving image quality. For the demonstration in this study, 20 4D-CTP dynamic images of suspected acute stroke patients were collected. Both the images that were and were not processed via the proposed method were compared. Each acquired image was objectively evaluated using contrast-to-noise and signal-to-noise ratios. The scores of the parameters assessed for the qualitative evaluation of image quality improved to an excellent rating (<i>p</i> < 0.05). Therefore, our SVD-based image-denoising technique improved the diagnostic value of images by improving their quality. The denoising technique and statistical evaluation can be utilized in various clinical applications to provide advanced medical services.https://www.mdpi.com/1424-8220/20/11/3063acute strokecomputed tomographyimage qualitysingular value decompositionGaussian noisecontrast-to-noise |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Wonseok Yang Jun-Yong Hong Jeong-Youn Kim Seung-ho Paik Seung Hyun Lee Ji-Su Park Gihyoun Lee Beop Min Kim Young-Jin Jung |
spellingShingle |
Wonseok Yang Jun-Yong Hong Jeong-Youn Kim Seung-ho Paik Seung Hyun Lee Ji-Su Park Gihyoun Lee Beop Min Kim Young-Jin Jung A Novel Singular Value Decomposition-Based Denoising Method in 4-Dimensional Computed Tomography of the Brain in Stroke Patients with Statistical Evaluation Sensors acute stroke computed tomography image quality singular value decomposition Gaussian noise contrast-to-noise |
author_facet |
Wonseok Yang Jun-Yong Hong Jeong-Youn Kim Seung-ho Paik Seung Hyun Lee Ji-Su Park Gihyoun Lee Beop Min Kim Young-Jin Jung |
author_sort |
Wonseok Yang |
title |
A Novel Singular Value Decomposition-Based Denoising Method in 4-Dimensional Computed Tomography of the Brain in Stroke Patients with Statistical Evaluation |
title_short |
A Novel Singular Value Decomposition-Based Denoising Method in 4-Dimensional Computed Tomography of the Brain in Stroke Patients with Statistical Evaluation |
title_full |
A Novel Singular Value Decomposition-Based Denoising Method in 4-Dimensional Computed Tomography of the Brain in Stroke Patients with Statistical Evaluation |
title_fullStr |
A Novel Singular Value Decomposition-Based Denoising Method in 4-Dimensional Computed Tomography of the Brain in Stroke Patients with Statistical Evaluation |
title_full_unstemmed |
A Novel Singular Value Decomposition-Based Denoising Method in 4-Dimensional Computed Tomography of the Brain in Stroke Patients with Statistical Evaluation |
title_sort |
novel singular value decomposition-based denoising method in 4-dimensional computed tomography of the brain in stroke patients with statistical evaluation |
publisher |
MDPI AG |
series |
Sensors |
issn |
1424-8220 |
publishDate |
2020-05-01 |
description |
Computed tomography (CT) is a widely used medical imaging modality for diagnosing various diseases. Among CT techniques, 4-dimensional CT perfusion (4D-CTP) of the brain is established in most centers for diagnosing strokes and is considered the gold standard for hyperacute stroke diagnosis. However, because the detrimental effects of high radiation doses from 4D-CTP may cause serious health risks in stroke survivors, our research team aimed to introduce a novel image-processing technique. Our singular value decomposition (SVD)-based image-processing technique can improve image quality, first, by separating several image components using SVD and, second, by reconstructing signal component images to remove noise, thereby improving image quality. For the demonstration in this study, 20 4D-CTP dynamic images of suspected acute stroke patients were collected. Both the images that were and were not processed via the proposed method were compared. Each acquired image was objectively evaluated using contrast-to-noise and signal-to-noise ratios. The scores of the parameters assessed for the qualitative evaluation of image quality improved to an excellent rating (<i>p</i> < 0.05). Therefore, our SVD-based image-denoising technique improved the diagnostic value of images by improving their quality. The denoising technique and statistical evaluation can be utilized in various clinical applications to provide advanced medical services. |
topic |
acute stroke computed tomography image quality singular value decomposition Gaussian noise contrast-to-noise |
url |
https://www.mdpi.com/1424-8220/20/11/3063 |
work_keys_str_mv |
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