Late-onset atopic dermatitis with nummular pattern

• Main Authors: Evelia Pautt-Lara, Laura Cala-Castro, Olga Harris, Ana Luiza Villarinho
• Format: Article
• Language: Spanish
• Published: Colegio Mexicano de Inmunología Clínica y Alergia, A.C. 2019-11-01
• Series: Revista Alergia México
• Subjects: dermatitis atópica; heterogeneidad clínica; dermatitis flexural; adultos
• Online Access: http://revistaalergia.mx/ojs/index.php/ram/article/view/552

Background: Adults with atopic dermatitis have had a persistent form in childhood or with an onset after the age of eighteen years. Late-onset atopic dermatitis may present with clinical heterogeneity and it often lacks the classic pattern of flexural dermatitis. Clinical case: A 26-year-old man with allergic rhinitis, with late-onset eczema, and an atypical nummular pattern on his trunk and limbs. The skin biopsy showed eczema-like lesions which, together with the patient’s personal history and laboratory abnormalities, allowed the diagnosis of the adult’s late-onset atopic dermatitis. Treatment with methotrexate was started and there was no response, which is why phototherapy was prescribed due to the dependence on systemic corticosteroids. Conclusion: Atypical presentations of atopic dermatitis in adults represent a clinical challenge. A personal history of atopy, sensitivity to aeroallergens, eosinophilia, and a cutaneous biopsy are essential to establish the diagnosis.