Follicular dendritic cell sarcoma: report of two cases and literature review

• Main Authors: Francisca E. M. M. Lima, Iago F. Jorge, Jacques Kauffman, Gunter Gerson, Maria do Patrocínio F. G. Beco, Juliana M. Cavalcante, Carlos Gustavo Hirth, Raimundo N. L. Neto
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Patologia Clínica 2015-08-01
• Series: Jornal Brasileiro de Patologia e Medicina Laboratorial
• Subjects: células dendríticas foliculares; neoplasias de células dendríticas; sarcoma de células dendríticas foliculares; patologia
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442015000400258&lng=en&tlng=en

ABSTRACTFollicular dendritic cell sarcoma is a rare neoplasm, first described in 1986 by Monda. Case 1: A female patient, 50-year-old performed abdominal computed tomography scan that detected a tumor lesion of 8.0 cm in the mesentery. She underwent resection of the lesion. Microscopic examination revealed epithelioid neoplasm, interspersed with lymphocytes, and positive immunohistochemical staining for CD21 and CD35. The patient underwent adjuvant chemotherapy. Case 2: A male patient, 21-year-old presented right-sided neck mass measuring 7.0 cm. The biopsy revealed proliferation of spindle cells, interspersed with inflammatory infiltrate and storiform arrangement, and positive immunohistochemical staining for CD21 and CD23. The patient underwent neoadjuvant radiotherapy and surgical resection.