Visualization of transepithelial passage of the immunogenic 33-residue peptide from alpha-2 gliadin in gluten-sensitive macaques.

Visualization of transepithelial passage of the immunogenic 33-residue peptide from alpha-2 gliadin in gluten-sensitive macaques.

Based on clinical, histopathological and serological similarities to human celiac disease (CD), we recently established the rhesus macaque model of gluten sensitivity. In this study, we further characterized this condition based on presence of anti-tissue transglutaminase 2 (TG2) antibodies, increas...

Full description

Bibliographic Details
Main Authors:	Kaushiki Mazumdar, Xavier Alvarez, Juan T Borda, Jason Dufour, Edith Martin, Michael T Bethune, Chaitan Khosla, Karol Sestak
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-04-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2856682?pdf=render

Similar Items

Transepithelial transport and enzymatic detoxification of gluten in gluten-sensitive rhesus macaques.
by: Michael T Bethune, et al.
Published: (2008-03-01)

Parallels between pathogens and gluten peptides in celiac sprue.
by: Michael T Bethune, et al.
Published: (2008-02-01)

The Effects of Reduced Gluten Barley Diet on Humoral and Cell-Mediated Systemic Immune Responses of Gluten-Sensitive Rhesus Macaques
by: Karol Sestak, et al.
Published: (2015-03-01)

A non-human primate model for gluten sensitivity.
by: Michael T Bethune, et al.
Published: (2008-02-01)

Toward the assessment of food toxicity for celiac patients: characterization of monoclonal antibodies to a main immunogenic gluten peptide.
by: Belén Morón, et al.
Published: (2008-05-01)

A food-grade enzyme preparation with modest gluten detoxification properties.
by: Jennifer Ehren, et al.
Published: (2009-07-01)

Beneficial Effects of Human Anti-Interleukin-15 Antibody in Gluten-Sensitive Rhesus Macaques with Celiac Disease
by: Karol Sestak, et al.
Published: (2018-07-01)

Improved xenobiotic metabolism and reduced susceptibility to cancer in gluten-sensitive macaques upon introduction of a gluten-free diet.
by: Karol Sestak, et al.
Published: (2011-04-01)

Supplementation of Reduced Gluten Barley Diet with Oral Prolyl Endopeptidase Effectively Abrogates Enteropathy-Associated Changes in Gluten-Sensitive Macaques
by: Karol Sestak, et al.
Published: (2016-06-01)

Size-Dependent Phagocytic Uptake and Immunogenicity of Gliadin Nanoparticles
by: Mohammed S. Alqahtani, et al.
Published: (2020-11-01)

Epithelial transport of immunogenic and toxic gliadin peptides in vitro.
by: Christian Zimmermann, et al.
Published: (2014-01-01)

Reduced-gliadin wheat bread: an alternative to the gluten-free diet for consumers suffering gluten-related pathologies.
by: Javier Gil-Humanes, et al.
Published: (2014-01-01)

Separation of gliadin peptides for investigation of the injurious agent(s) in gluten sensitive enteropathy
by: Jasti, Sunitha
Published: (2014)

BL-7010 demonstrates specific binding to gliadin and reduces gluten-associated pathology in a chronic mouse model of gliadin sensitivity.
by: Justin L McCarville, et al.
Published: (2014-01-01)

Reducing the Immunogenic Potential of Wheat Flour: Silencing of Alpha Gliadin Genes in a U.S. Wheat Cultivar
by: Susan B. Altenbach, et al.
Published: (2020-02-01)

Microscopic and Thermal Characteristics of Experimental Models of Starch, Gliadins, Glutenins and Gluten from Semolina
by: A. Romano, et al.
Published: (2015-05-01)

Effects of Physical and Chemical Factors on the Structure of Gluten, Gliadins and Glutenins as Studied with Spectroscopic Methods
by: Konrad Kłosok, et al.
Published: (2021-01-01)

The α-Gliadins in Bread Wheat: Effect of Nitrogen Treatment on the Expression of the Major Celiac Disease Immunogenic Complex in Two RNAi Low-Gliadin Lines
by: Susana Sánchez-León, et al.
Published: (2021-04-01)

Comparative Analysis of in vitro Digestibility and Immunogenicity of Gliadin Proteins From Durum and Einkorn Wheat
by: Luigia Di Stasio, et al.
Published: (2020-05-01)

Immunogenicity Characterization of Two Ancient Wheat α-Gliadin Peptides Related to Coeliac Disease
by: Paul J. Ciclitira, et al.
Published: (2009-12-01)

Dietary Gluten and Neurodegeneration: A Case for Preclinical Studies
by: Mahesh Mohan, et al.
Published: (2020-07-01)

Dietary Gluten-Induced Gut Dysbiosis Is Accompanied by Selective Upregulation of microRNAs with Intestinal Tight Junction and Bacteria-Binding Motifs in Rhesus Macaque Model of Celiac Disease
by: Mahesh Mohan, et al.
Published: (2016-10-01)

Sourdough Fermentation of Wheat Flour does not Prevent the Interaction of Transglutaminase 2 with α2-Gliadin or Gluten
by: Niklas Engström, et al.
Published: (2015-03-01)

Down-regulating γ-gliadins in bread wheat leads to non-specific increases in other gluten proteins and has no major effect on dough gluten strength.
by: Fernando Pistón, et al.
Published: (2011-01-01)

Gliadin-Specific T-Cells Mobilized in the Peripheral Blood of Coeliac Patients by Short Oral Gluten Challenge: Clinical Applications
by: Stefania Picascia, et al.
Published: (2015-12-01)

Gliadin fragments and a specific gliadin 33-mer peptide close KATP channels and induce insulin secretion in INS-1E cells and rat islets of langerhans.
by: Morten Dall, et al.
Published: (2013-01-01)

Antibody reactivity in patients with IgE-mediated wheat allergy to various subunits and fractions of gluten and non-gluten proteins from ω-gliadin-free wheat genotypes
by: Andrzej Skoczowski, et al.
Published: (2017-05-01)

Effect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity
by: Justin Hollon, et al.
Published: (2015-02-01)

Probiotics Supplements Reduce ER Stress and Gut Inflammation Associated with Gliadin Intake in a Mouse Model of Gluten Sensitivity
by: Eleonora Ferrari, et al.
Published: (2021-04-01)

Porcine intestinal epithelial barrier disruption by the <it>Fusarium</it> mycotoxins deoxynivalenol and T-2 toxin promotes transepithelial passage of doxycycline and paromomycin
by: Goossens Joline, et al.
Published: (2012-12-01)

Dynamics and Considerations in the Determination of the Excretion of Gluten Immunogenic Peptides in Urine: Individual Variability at Low Gluten Intake
by: Laura Coto, et al.
Published: (2021-07-01)

Outlook for coeliac disease patients: towards bread wheat with hypoimmunogenic gluten by gene editing of α- and γ-gliadin gene families
by: Aurélie Jouanin, et al.
Published: (2019-08-01)

Surfactant Protein D Reverses the Gene Signature of Transepithelial HIV-1 Passage and Restricts the Viral Transfer Across the Vaginal Barrier
by: Hrishikesh Pandit, et al.
Published: (2019-03-01)

Freshwater sponges have functional, sealing epithelia with high transepithelial resistance and negative transepithelial potential.
by: Emily D M Adams, et al.
Published: (2010-01-01)

Celiac Immunogenic Potential of α-Gliadin Epitope Variants from <i>Triticum</i> and <i>Aegilops</i> Species
by: Ángela Ruiz-Carnicer, et al.
Published: (2019-01-01)

Pharmacokinetics and immunogenicity of broadly neutralizing HIV monoclonal antibodies in macaques.
by: Yvonne Rosenberg, et al.
Published: (2015-01-01)

The Dietary Intervention of Transgenic Low-Gliadin Wheat Bread in Patients with Non-Celiac Gluten Sensitivity (NCGS) Showed No Differences with Gluten Free Diet (GFD) but Provides Better Gut Microbiota Profile
by: Carmen Haro, et al.
Published: (2018-12-01)

A Case Study of the Response of Immunogenic Gluten Peptides to Sourdough Proteolysis
by: Olivia J. Ogilvie, et al.
Published: (2021-06-01)

Preparation, Properties, Protein Cross-Linking and Biodegradability of Plasticizer-Solvent Free Hemp Fibre Reinforced Wheat Gluten, Glutenin, and Gliadin Composites
by: Faraz Muneer, et al.
Published: (2014-07-01)

A new microbial gluten-degrading prolyl endopeptidase: Potential application in celiac disease to reduce gluten immunogenic peptides.
by: María de Lourdes Moreno Amador, et al.
Published: (2019-01-01)

Cannot write session to /tmp/vufind_sessions/sess_9kqmjd398gqc4b4n231t150uu9