Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations.

Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations.

While nucleosome positioning on eukaryotic genome play important roles for genetic regulation, molecular mechanisms of nucleosome positioning and sliding along DNA are not well understood. Here we investigated thermally-activated spontaneous nucleosome sliding mechanisms developing and applying a co...

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Bibliographic Details
Main Authors: Toru Niina, Giovanni B Brandani, Cheng Tan, Shoji Takada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5728581?pdf=render

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