Rifampicin exposure reveals within-host Mycobacterium tuberculosis diversity in patients with delayed culture conversion.
Mycobacterium tuberculosis (Mtb) genetic micro-diversity in clinical isolates may underline mycobacterial adaptation to tuberculosis (TB) infection and provide insights to anti-TB treatment response and emergence of resistance. Herein we followed within-host evolution of Mtb clinical isolates in two...
Main Authors: | Charlotte Genestet, Elisabeth Hodille, Alexia Barbry, Jean-Luc Berland, Jonathan Hoffmann, Emilie Westeel, Fabiola Bastian, Michel Guichardant, Samuel Venner, Gérard Lina, Christophe Ginevra, Florence Ader, Sylvain Goutelle, Oana Dumitrescu |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-06-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1009643 |
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