Selenium plasma levels in hemodialysis patients: Comparison between North and Southeast of Brazil
Introduction: Patients with chronic kidney disease present selenium (Se) plasma deficiency which is an essential trace element with important biological functions and, the best known biological role is attributed to its presence in the antioxidant enzyme, glutathione peroxidase (GPx). The Se content...
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Sociedade Brasileira de Nefrologia
2014-12-01
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doaj-567c466fb90b49be8cecd1fecdbb9c652020-11-25T00:40:28ZengSociedade Brasileira de NefrologiaBrazilian Journal of Nephrology2175-82392014-12-0136449049510.5935/0101-2800.20140070S0101-28002014000400490Selenium plasma levels in hemodialysis patients: Comparison between North and Southeast of BrazilMilena Barcza Stockler-PintoOlaf MalmSuellen Regina Geraldo AzevedoNajla Elias FaragePaulo Renato DornelesSilvia Maria Franciscato CozzolinoDenise MafraIntroduction: Patients with chronic kidney disease present selenium (Se) plasma deficiency which is an essential trace element with important biological functions and, the best known biological role is attributed to its presence in the antioxidant enzyme, glutathione peroxidase (GPx). The Se content of foods depends on soil and some authors have suggested that Amazon soil (North Brazilian region) has high Se concentrations when compared to other regions of Brazil. Objective: The objective of this work was to compare the Se status in hemodialysis (HD) patients from North and Southeast of Brazil. Methods: Thirty-eight patients from Southeast region (22 men and 16 women, 15% diabetic, 53.5 ± 26.4 yrs) were compared to 40 patients from North region (28 men and 12 women, 22.5% diabetic, 63.5 ± 11.9 yrs). Se in plasma was determined through atomic absorption spectrophotometry with hydride generation. Results: The plasma Se levels in patients from Southeast region were significantly lower (17.5 ± 11.9 μg/L) when compared to patients from the North (37.1 ± 15.8 μg/L) (p < 0.001). However, both patient groups presented low Se plasma levels when compared to recommended values (60- 120 μg/L). There was no correlation between plasma Se levels and analyzed parameters. Conclusion: We concluded that patients from North (Amazon) region present higher plasma Se levels when compared to the patients from Southeast of Brazil. However, independently of the region, HD patients presented Se deficiency.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002014000400490&lng=en&tlng=enBrasilhemodiáliseselênio |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Milena Barcza Stockler-Pinto Olaf Malm Suellen Regina Geraldo Azevedo Najla Elias Farage Paulo Renato Dorneles Silvia Maria Franciscato Cozzolino Denise Mafra |
spellingShingle |
Milena Barcza Stockler-Pinto Olaf Malm Suellen Regina Geraldo Azevedo Najla Elias Farage Paulo Renato Dorneles Silvia Maria Franciscato Cozzolino Denise Mafra Selenium plasma levels in hemodialysis patients: Comparison between North and Southeast of Brazil Brazilian Journal of Nephrology Brasil hemodiálise selênio |
author_facet |
Milena Barcza Stockler-Pinto Olaf Malm Suellen Regina Geraldo Azevedo Najla Elias Farage Paulo Renato Dorneles Silvia Maria Franciscato Cozzolino Denise Mafra |
author_sort |
Milena Barcza Stockler-Pinto |
title |
Selenium plasma levels in hemodialysis patients: Comparison between North and Southeast of Brazil |
title_short |
Selenium plasma levels in hemodialysis patients: Comparison between North and Southeast of Brazil |
title_full |
Selenium plasma levels in hemodialysis patients: Comparison between North and Southeast of Brazil |
title_fullStr |
Selenium plasma levels in hemodialysis patients: Comparison between North and Southeast of Brazil |
title_full_unstemmed |
Selenium plasma levels in hemodialysis patients: Comparison between North and Southeast of Brazil |
title_sort |
selenium plasma levels in hemodialysis patients: comparison between north and southeast of brazil |
publisher |
Sociedade Brasileira de Nefrologia |
series |
Brazilian Journal of Nephrology |
issn |
2175-8239 |
publishDate |
2014-12-01 |
description |
Introduction: Patients with chronic kidney disease present selenium (Se) plasma deficiency which is an essential trace element with important biological functions and, the best known biological role is attributed to its presence in the antioxidant enzyme, glutathione peroxidase (GPx). The Se content of foods depends on soil and some authors have suggested that Amazon soil (North Brazilian region) has high Se concentrations when compared to other regions of Brazil. Objective: The objective of this work was to compare the Se status in hemodialysis (HD) patients from North and Southeast of Brazil. Methods: Thirty-eight patients from Southeast region (22 men and 16 women, 15% diabetic, 53.5 ± 26.4 yrs) were compared to 40 patients from North region (28 men and 12 women, 22.5% diabetic, 63.5 ± 11.9 yrs). Se in plasma was determined through atomic absorption spectrophotometry with hydride generation. Results: The plasma Se levels in patients from Southeast region were significantly lower (17.5 ± 11.9 μg/L) when compared to patients from the North (37.1 ± 15.8 μg/L) (p < 0.001). However, both patient groups presented low Se plasma levels when compared to recommended values (60- 120 μg/L). There was no correlation between plasma Se levels and analyzed parameters. Conclusion: We concluded that patients from North (Amazon) region present higher plasma Se levels when compared to the patients from Southeast of Brazil. However, independently of the region, HD patients presented Se deficiency. |
topic |
Brasil hemodiálise selênio |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002014000400490&lng=en&tlng=en |
work_keys_str_mv |
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