Impact of insecticide-treated nets on wild pyrethroid resistant <it>Anopheles epiroticus </it>population from southern Vietnam tested in experimental huts
<p>Abstract</p> <p>Background</p> <p>In this study, the efficacy of insecticide-treated nets was evaluated in terms of deterrence, blood-feeding inhibition, induced exophily and mortality on a wild resistant population of <it>Anopheles epiroticus </it>in sou...
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doaj-567d11a8fa774204862bbb8c5a5340be2020-11-24T21:44:58ZengBMCMalaria Journal1475-28752009-10-018124810.1186/1475-2875-8-248Impact of insecticide-treated nets on wild pyrethroid resistant <it>Anopheles epiroticus </it>population from southern Vietnam tested in experimental hutsTrung HoSpeybroeck NikoBerkvens DirkChinh VuVan Bortel WimCoosemans Marc<p>Abstract</p> <p>Background</p> <p>In this study, the efficacy of insecticide-treated nets was evaluated in terms of deterrence, blood-feeding inhibition, induced exophily and mortality on a wild resistant population of <it>Anopheles epiroticus </it>in southern Vietnam, in order to gain insight into the operational consequences of the insecticide resistance observed in this malaria vector in the Mekong delta.</p> <p>Method</p> <p>An experimental station, based on the model of West Africa and adapted to the behaviour of the target species, was built in southern Vietnam. The study design was adapted from the WHO phase 2 guidelines. The study arms included a conventionally treated polyester net (CTN) with deltamethrin washed just before exhaustion, the WHO recommended long-lasting insecticidal net (LLIN) PermaNet 2.0<sup>® </sup>unwashed and 20 times washed and PermaNet 3.0<sup>®</sup>, designed for the control of pyrethroid resistant vectors, unwashed and 20 times washed.</p> <p>Results</p> <p>The nets still provided personal protection against the resistant <it>An. epiroticus </it>population. The personal protection ranged from 67% for deltamethrin CTN to 85% for unwashed PermaNet 3.0. Insecticide resistance in the <it>An. epiroticus </it>mosquitoes did not seem to alter the deterrent effect of pyrethroids. A significant higher mortality was still observed among the treatment arms despite the fact that the <it>An. epiroticus </it>population is resistant against the tested insecticides.</p> <p>Conclusion</p> <p>This study shows that CTN and LLINs still protect individuals against a pyrethroid resistant malaria vector from the Mekong region, where insecticide resistance is caused by a metabolic mechanism. In the light of a possible elimination of malaria from the Mekong region these insights in operational consequences of the insecticide resistance on control tools is of upmost importance.</p> http://www.malariajournal.com/content/8/1/248 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Trung Ho Speybroeck Niko Berkvens Dirk Chinh Vu Van Bortel Wim Coosemans Marc |
spellingShingle |
Trung Ho Speybroeck Niko Berkvens Dirk Chinh Vu Van Bortel Wim Coosemans Marc Impact of insecticide-treated nets on wild pyrethroid resistant <it>Anopheles epiroticus </it>population from southern Vietnam tested in experimental huts Malaria Journal |
author_facet |
Trung Ho Speybroeck Niko Berkvens Dirk Chinh Vu Van Bortel Wim Coosemans Marc |
author_sort |
Trung Ho |
title |
Impact of insecticide-treated nets on wild pyrethroid resistant <it>Anopheles epiroticus </it>population from southern Vietnam tested in experimental huts |
title_short |
Impact of insecticide-treated nets on wild pyrethroid resistant <it>Anopheles epiroticus </it>population from southern Vietnam tested in experimental huts |
title_full |
Impact of insecticide-treated nets on wild pyrethroid resistant <it>Anopheles epiroticus </it>population from southern Vietnam tested in experimental huts |
title_fullStr |
Impact of insecticide-treated nets on wild pyrethroid resistant <it>Anopheles epiroticus </it>population from southern Vietnam tested in experimental huts |
title_full_unstemmed |
Impact of insecticide-treated nets on wild pyrethroid resistant <it>Anopheles epiroticus </it>population from southern Vietnam tested in experimental huts |
title_sort |
impact of insecticide-treated nets on wild pyrethroid resistant <it>anopheles epiroticus </it>population from southern vietnam tested in experimental huts |
publisher |
BMC |
series |
Malaria Journal |
issn |
1475-2875 |
publishDate |
2009-10-01 |
description |
<p>Abstract</p> <p>Background</p> <p>In this study, the efficacy of insecticide-treated nets was evaluated in terms of deterrence, blood-feeding inhibition, induced exophily and mortality on a wild resistant population of <it>Anopheles epiroticus </it>in southern Vietnam, in order to gain insight into the operational consequences of the insecticide resistance observed in this malaria vector in the Mekong delta.</p> <p>Method</p> <p>An experimental station, based on the model of West Africa and adapted to the behaviour of the target species, was built in southern Vietnam. The study design was adapted from the WHO phase 2 guidelines. The study arms included a conventionally treated polyester net (CTN) with deltamethrin washed just before exhaustion, the WHO recommended long-lasting insecticidal net (LLIN) PermaNet 2.0<sup>® </sup>unwashed and 20 times washed and PermaNet 3.0<sup>®</sup>, designed for the control of pyrethroid resistant vectors, unwashed and 20 times washed.</p> <p>Results</p> <p>The nets still provided personal protection against the resistant <it>An. epiroticus </it>population. The personal protection ranged from 67% for deltamethrin CTN to 85% for unwashed PermaNet 3.0. Insecticide resistance in the <it>An. epiroticus </it>mosquitoes did not seem to alter the deterrent effect of pyrethroids. A significant higher mortality was still observed among the treatment arms despite the fact that the <it>An. epiroticus </it>population is resistant against the tested insecticides.</p> <p>Conclusion</p> <p>This study shows that CTN and LLINs still protect individuals against a pyrethroid resistant malaria vector from the Mekong region, where insecticide resistance is caused by a metabolic mechanism. In the light of a possible elimination of malaria from the Mekong region these insights in operational consequences of the insecticide resistance on control tools is of upmost importance.</p> |
url |
http://www.malariajournal.com/content/8/1/248 |
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