Recovery of Visual Function after Administration of Dabigatran Etexilate
A 46-year-old Caucasian female underwent pars plana vitrectomy (ppv) for retinal detachment. After the procedure, the patient could only distinguish hand movements; the condition was tentatively diagnosed as nonarteritic anterior ischemic optic neuropathy. Conventional treatment with systemic cortic...
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doaj-5683009e422842d9a822b4ea01d558e72020-11-24T20:48:12ZengKarger PublishersCase Reports in Ophthalmology1663-26992014-08-015226226610.1159/000365961365961Recovery of Visual Function after Administration of Dabigatran EtexilateCarl-Ludwig SchönfeldMarie FischerPeter DistelmaierSebastian PhilippPatrick PaquetKatharina HallerLinda MeyerA 46-year-old Caucasian female underwent pars plana vitrectomy (ppv) for retinal detachment. After the procedure, the patient could only distinguish hand movements; the condition was tentatively diagnosed as nonarteritic anterior ischemic optic neuropathy. Conventional treatment with systemic corticosteroids and acetylsalicylic acid was ineffective and yielded substantial steroid-related side effects. Additional administration of 2 × 110 mg dabigatran etexilate (Pradaxa®), a novel direct thrombin inhibitor, resulted in a prompt and marked improvement of visual acuity, which indicated improved blood flow in the central vessels of the optic nerve. Dabigatran etexilate may provide a promising alternative for the treatment of postprocedural vision loss after ppv.http://www.karger.com/Article/FullText/365961Complications, postoperativeAntithrombotic agentsDabigatran etexilateVisual lossPars plana vitrectomy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Carl-Ludwig Schönfeld Marie Fischer Peter Distelmaier Sebastian Philipp Patrick Paquet Katharina Haller Linda Meyer |
spellingShingle |
Carl-Ludwig Schönfeld Marie Fischer Peter Distelmaier Sebastian Philipp Patrick Paquet Katharina Haller Linda Meyer Recovery of Visual Function after Administration of Dabigatran Etexilate Case Reports in Ophthalmology Complications, postoperative Antithrombotic agents Dabigatran etexilate Visual loss Pars plana vitrectomy |
author_facet |
Carl-Ludwig Schönfeld Marie Fischer Peter Distelmaier Sebastian Philipp Patrick Paquet Katharina Haller Linda Meyer |
author_sort |
Carl-Ludwig Schönfeld |
title |
Recovery of Visual Function after Administration of Dabigatran Etexilate |
title_short |
Recovery of Visual Function after Administration of Dabigatran Etexilate |
title_full |
Recovery of Visual Function after Administration of Dabigatran Etexilate |
title_fullStr |
Recovery of Visual Function after Administration of Dabigatran Etexilate |
title_full_unstemmed |
Recovery of Visual Function after Administration of Dabigatran Etexilate |
title_sort |
recovery of visual function after administration of dabigatran etexilate |
publisher |
Karger Publishers |
series |
Case Reports in Ophthalmology |
issn |
1663-2699 |
publishDate |
2014-08-01 |
description |
A 46-year-old Caucasian female underwent pars plana vitrectomy (ppv) for retinal detachment. After the procedure, the patient could only distinguish hand movements; the condition was tentatively diagnosed as nonarteritic anterior ischemic optic neuropathy. Conventional treatment with systemic corticosteroids and acetylsalicylic acid was ineffective and yielded substantial steroid-related side effects. Additional administration of 2 × 110 mg dabigatran etexilate (Pradaxa®), a novel direct thrombin inhibitor, resulted in a prompt and marked improvement of visual acuity, which indicated improved blood flow in the central vessels of the optic nerve. Dabigatran etexilate may provide a promising alternative for the treatment of postprocedural vision loss after ppv. |
topic |
Complications, postoperative Antithrombotic agents Dabigatran etexilate Visual loss Pars plana vitrectomy |
url |
http://www.karger.com/Article/FullText/365961 |
work_keys_str_mv |
AT carlludwigschonfeld recoveryofvisualfunctionafteradministrationofdabigatranetexilate AT mariefischer recoveryofvisualfunctionafteradministrationofdabigatranetexilate AT peterdistelmaier recoveryofvisualfunctionafteradministrationofdabigatranetexilate AT sebastianphilipp recoveryofvisualfunctionafteradministrationofdabigatranetexilate AT patrickpaquet recoveryofvisualfunctionafteradministrationofdabigatranetexilate AT katharinahaller recoveryofvisualfunctionafteradministrationofdabigatranetexilate AT lindameyer recoveryofvisualfunctionafteradministrationofdabigatranetexilate |
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