Leveraging natural history biorepositories as a global, decentralized, pathogen surveillance network.
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic reveals a major gap in global biosecurity infrastructure: a lack of publicly available biological samples representative across space, time, and taxonomic diversity. The shortfall, in this case for vertebrates, prevents accura...
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doaj-5692e7085d2347df9e679eff74fee4cb2021-06-19T04:32:15ZengPublic Library of Science (PLoS)PLoS Pathogens1553-73661553-73742021-06-01176e100958310.1371/journal.ppat.1009583Leveraging natural history biorepositories as a global, decentralized, pathogen surveillance network.Jocelyn P ColellaJohn BatesSantiago F BurneoM Alejandra CamachoCarlos Carrion BonillaIsabel ConstableGuillermo D'ElíaJonathan L DunnumStephen GreimanEric P HobergEnrique LessaSchuyler W LiphardtManuela Londoño-GaviriaElizabeth LososHolly L LutzNicté Ordóñez GarzaA Townsend PetersonMaría Laura MartinCamila C RibasBruce StrumingerFernando Torres-PérezCody W ThompsonMarcelo WekslerJoseph A CookThe Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic reveals a major gap in global biosecurity infrastructure: a lack of publicly available biological samples representative across space, time, and taxonomic diversity. The shortfall, in this case for vertebrates, prevents accurate and rapid identification and monitoring of emerging pathogens and their reservoir host(s) and precludes extended investigation of ecological, evolutionary, and environmental associations that lead to human infection or spillover. Natural history museum biorepositories form the backbone of a critically needed, decentralized, global network for zoonotic pathogen surveillance, yet this infrastructure remains marginally developed, underutilized, underfunded, and disconnected from public health initiatives. Proactive detection and mitigation for emerging infectious diseases (EIDs) requires expanded biodiversity infrastructure and training (particularly in biodiverse and lower income countries) and new communication pipelines that connect biorepositories and biomedical communities. To this end, we highlight a novel adaptation of Project ECHO's virtual community of practice model: Museums and Emerging Pathogens in the Americas (MEPA). MEPA is a virtual network aimed at fostering communication, coordination, and collaborative problem-solving among pathogen researchers, public health officials, and biorepositories in the Americas. MEPA now acts as a model of effective international, interdisciplinary collaboration that can and should be replicated in other biodiversity hotspots. We encourage deposition of wildlife specimens and associated data with public biorepositories, regardless of original collection purpose, and urge biorepositories to embrace new specimen sources, types, and uses to maximize strategic growth and utility for EID research. Taxonomically, geographically, and temporally deep biorepository archives serve as the foundation of a proactive and increasingly predictive approach to zoonotic spillover, risk assessment, and threat mitigation.https://doi.org/10.1371/journal.ppat.1009583 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jocelyn P Colella John Bates Santiago F Burneo M Alejandra Camacho Carlos Carrion Bonilla Isabel Constable Guillermo D'Elía Jonathan L Dunnum Stephen Greiman Eric P Hoberg Enrique Lessa Schuyler W Liphardt Manuela Londoño-Gaviria Elizabeth Losos Holly L Lutz Nicté Ordóñez Garza A Townsend Peterson María Laura Martin Camila C Ribas Bruce Struminger Fernando Torres-Pérez Cody W Thompson Marcelo Weksler Joseph A Cook |
spellingShingle |
Jocelyn P Colella John Bates Santiago F Burneo M Alejandra Camacho Carlos Carrion Bonilla Isabel Constable Guillermo D'Elía Jonathan L Dunnum Stephen Greiman Eric P Hoberg Enrique Lessa Schuyler W Liphardt Manuela Londoño-Gaviria Elizabeth Losos Holly L Lutz Nicté Ordóñez Garza A Townsend Peterson María Laura Martin Camila C Ribas Bruce Struminger Fernando Torres-Pérez Cody W Thompson Marcelo Weksler Joseph A Cook Leveraging natural history biorepositories as a global, decentralized, pathogen surveillance network. PLoS Pathogens |
author_facet |
Jocelyn P Colella John Bates Santiago F Burneo M Alejandra Camacho Carlos Carrion Bonilla Isabel Constable Guillermo D'Elía Jonathan L Dunnum Stephen Greiman Eric P Hoberg Enrique Lessa Schuyler W Liphardt Manuela Londoño-Gaviria Elizabeth Losos Holly L Lutz Nicté Ordóñez Garza A Townsend Peterson María Laura Martin Camila C Ribas Bruce Struminger Fernando Torres-Pérez Cody W Thompson Marcelo Weksler Joseph A Cook |
author_sort |
Jocelyn P Colella |
title |
Leveraging natural history biorepositories as a global, decentralized, pathogen surveillance network. |
title_short |
Leveraging natural history biorepositories as a global, decentralized, pathogen surveillance network. |
title_full |
Leveraging natural history biorepositories as a global, decentralized, pathogen surveillance network. |
title_fullStr |
Leveraging natural history biorepositories as a global, decentralized, pathogen surveillance network. |
title_full_unstemmed |
Leveraging natural history biorepositories as a global, decentralized, pathogen surveillance network. |
title_sort |
leveraging natural history biorepositories as a global, decentralized, pathogen surveillance network. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS Pathogens |
issn |
1553-7366 1553-7374 |
publishDate |
2021-06-01 |
description |
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic reveals a major gap in global biosecurity infrastructure: a lack of publicly available biological samples representative across space, time, and taxonomic diversity. The shortfall, in this case for vertebrates, prevents accurate and rapid identification and monitoring of emerging pathogens and their reservoir host(s) and precludes extended investigation of ecological, evolutionary, and environmental associations that lead to human infection or spillover. Natural history museum biorepositories form the backbone of a critically needed, decentralized, global network for zoonotic pathogen surveillance, yet this infrastructure remains marginally developed, underutilized, underfunded, and disconnected from public health initiatives. Proactive detection and mitigation for emerging infectious diseases (EIDs) requires expanded biodiversity infrastructure and training (particularly in biodiverse and lower income countries) and new communication pipelines that connect biorepositories and biomedical communities. To this end, we highlight a novel adaptation of Project ECHO's virtual community of practice model: Museums and Emerging Pathogens in the Americas (MEPA). MEPA is a virtual network aimed at fostering communication, coordination, and collaborative problem-solving among pathogen researchers, public health officials, and biorepositories in the Americas. MEPA now acts as a model of effective international, interdisciplinary collaboration that can and should be replicated in other biodiversity hotspots. We encourage deposition of wildlife specimens and associated data with public biorepositories, regardless of original collection purpose, and urge biorepositories to embrace new specimen sources, types, and uses to maximize strategic growth and utility for EID research. Taxonomically, geographically, and temporally deep biorepository archives serve as the foundation of a proactive and increasingly predictive approach to zoonotic spillover, risk assessment, and threat mitigation. |
url |
https://doi.org/10.1371/journal.ppat.1009583 |
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