Coagulation phenotypes in sepsis and effects of recombinant human thrombomodulin: an analysis of three multicentre observational studies
Abstract Background A recent randomised trial showed that recombinant thrombomodulin did not benefit patients who had sepsis with coagulopathy and organ dysfunction. Several recent studies suggested presence of clinical phenotypes in patients with sepsis and heterogenous treatment effects across dif...
Main Authors: | Daisuke Kudo, Tadahiro Goto, Ryo Uchimido, Mineji Hayakawa, Kazuma Yamakawa, Toshikazu Abe, Atsushi Shiraishi, Shigeki Kushimoto |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | Critical Care |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13054-021-03541-5 |
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