Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression

Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression

To determine the dynamics of allelic-specific expression during mouse development, we analyzed RNA-seq data from 23 F1 tissues from different developmental stages, including 19 female tissues allowing X chromosome inactivation (XCI) escapers to also be detected. We demonstrate that allelic expressio...

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Bibliographic Details
Main Authors: Daniel Andergassen, Christoph P Dotter, Daniel Wenzel, Verena Sigl, Philipp C Bammer, Markus Muckenhuber, Daniela Mayer, Tomasz M Kulinski, Hans-Christian Theussl, Josef M Penninger, Christoph Bock, Denise P Barlow, Florian M Pauler, Quanah J Hudson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
genomic imprinting
XCI escapers
allelic expression
enhancer
H3K27ac
strain-biased expression
Online Access:https://elifesciences.org/articles/25125

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