Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects
Quercetin is a kind of flavonoid compounds that comes from nature and is widely existed in the daily diet. Previous studies have found that quercetin has many effects such as anti-inflammatory, anti-oxidation and anti-cancer. Both in vivo and in vitro experiments have demonstrated that quercetin can...
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doaj-56b966f9c93b4f24a1583de76600a44b2021-05-20T07:39:27ZengElsevierBiomedicine & Pharmacotherapy0753-33222020-01-01121109604Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effectsSi-Min Tang0Xue-Ting Deng1Jian Zhou2Quan-Peng Li3Xian-Xiu Ge4Lin Miao5The Second People's Hospital of Huai’an, Huai’an, China; Medical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, ChinaMedical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, ChinaMedical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China; Department of Gastrointestinal Endoscopy, Nanjing Medical University, Nanjing, ChinaMedical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China; Department of Gastrointestinal Endoscopy, Nanjing Medical University, Nanjing, ChinaMedical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China; Department of Gastrointestinal Endoscopy, Nanjing Medical University, Nanjing, ChinaMedical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China; Department of Gastrointestinal Endoscopy, Nanjing Medical University, Nanjing, China; Corresponding author at: Medical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China.Quercetin is a kind of flavonoid compounds that comes from nature and is widely existed in the daily diet. Previous studies have found that quercetin has many effects such as anti-inflammatory, anti-oxidation and anti-cancer. Both in vivo and in vitro experiments have demonstrated that quercetin can exert anti-tumor effects by altering cell cycle progression, inhibiting cell proliferation, promoting apoptosis, inhibiting angiogenesis and metastasis progression, and affecting autophagy. This review summarizes the evidence for the pharmacological potential and inhibition of quercetin on cancers, supporting the viewpoint that quercetin should be adequately considered as a therapeutic agent against various cancers.http://www.sciencedirect.com/science/article/pii/S0753332219352266QuercetinCancerInhibitory effect |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Si-Min Tang Xue-Ting Deng Jian Zhou Quan-Peng Li Xian-Xiu Ge Lin Miao |
spellingShingle |
Si-Min Tang Xue-Ting Deng Jian Zhou Quan-Peng Li Xian-Xiu Ge Lin Miao Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects Biomedicine & Pharmacotherapy Quercetin Cancer Inhibitory effect |
author_facet |
Si-Min Tang Xue-Ting Deng Jian Zhou Quan-Peng Li Xian-Xiu Ge Lin Miao |
author_sort |
Si-Min Tang |
title |
Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects |
title_short |
Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects |
title_full |
Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects |
title_fullStr |
Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects |
title_full_unstemmed |
Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects |
title_sort |
pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects |
publisher |
Elsevier |
series |
Biomedicine & Pharmacotherapy |
issn |
0753-3322 |
publishDate |
2020-01-01 |
description |
Quercetin is a kind of flavonoid compounds that comes from nature and is widely existed in the daily diet. Previous studies have found that quercetin has many effects such as anti-inflammatory, anti-oxidation and anti-cancer. Both in vivo and in vitro experiments have demonstrated that quercetin can exert anti-tumor effects by altering cell cycle progression, inhibiting cell proliferation, promoting apoptosis, inhibiting angiogenesis and metastasis progression, and affecting autophagy. This review summarizes the evidence for the pharmacological potential and inhibition of quercetin on cancers, supporting the viewpoint that quercetin should be adequately considered as a therapeutic agent against various cancers. |
topic |
Quercetin Cancer Inhibitory effect |
url |
http://www.sciencedirect.com/science/article/pii/S0753332219352266 |
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