Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects

Quercetin is a kind of flavonoid compounds that comes from nature and is widely existed in the daily diet. Previous studies have found that quercetin has many effects such as anti-inflammatory, anti-oxidation and anti-cancer. Both in vivo and in vitro experiments have demonstrated that quercetin can...

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Main Authors:	Si-Min Tang, Xue-Ting Deng, Jian Zhou, Quan-Peng Li, Xian-Xiu Ge, Lin Miao
Format:	Article
Language:	English
Published:	Elsevier 2020-01-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	Quercetin Cancer Inhibitory effect
Online Access:	http://www.sciencedirect.com/science/article/pii/S0753332219352266

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spelling	doaj-56b966f9c93b4f24a1583de76600a44b2021-05-20T07:39:27ZengElsevierBiomedicine & Pharmacotherapy0753-33222020-01-01121109604Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effectsSi-Min Tang0Xue-Ting Deng1Jian Zhou2Quan-Peng Li3Xian-Xiu Ge4Lin Miao5The Second People's Hospital of Huai’an, Huai’an, China; Medical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, ChinaMedical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, ChinaMedical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China; Department of Gastrointestinal Endoscopy, Nanjing Medical University, Nanjing, ChinaMedical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China; Department of Gastrointestinal Endoscopy, Nanjing Medical University, Nanjing, ChinaMedical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China; Department of Gastrointestinal Endoscopy, Nanjing Medical University, Nanjing, ChinaMedical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China; Department of Gastrointestinal Endoscopy, Nanjing Medical University, Nanjing, China; Corresponding author at: Medical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China.Quercetin is a kind of flavonoid compounds that comes from nature and is widely existed in the daily diet. Previous studies have found that quercetin has many effects such as anti-inflammatory, anti-oxidation and anti-cancer. Both in vivo and in vitro experiments have demonstrated that quercetin can exert anti-tumor effects by altering cell cycle progression, inhibiting cell proliferation, promoting apoptosis, inhibiting angiogenesis and metastasis progression, and affecting autophagy. This review summarizes the evidence for the pharmacological potential and inhibition of quercetin on cancers, supporting the viewpoint that quercetin should be adequately considered as a therapeutic agent against various cancers.http://www.sciencedirect.com/science/article/pii/S0753332219352266QuercetinCancerInhibitory effect
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Si-Min Tang Xue-Ting Deng Jian Zhou Quan-Peng Li Xian-Xiu Ge Lin Miao
spellingShingle	Si-Min Tang Xue-Ting Deng Jian Zhou Quan-Peng Li Xian-Xiu Ge Lin Miao Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects Biomedicine & Pharmacotherapy Quercetin Cancer Inhibitory effect
author_facet	Si-Min Tang Xue-Ting Deng Jian Zhou Quan-Peng Li Xian-Xiu Ge Lin Miao
author_sort	Si-Min Tang
title	Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects
title_short	Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects
title_full	Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects
title_fullStr	Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects
title_full_unstemmed	Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects
title_sort	pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects
publisher	Elsevier
series	Biomedicine & Pharmacotherapy
issn	0753-3322
publishDate	2020-01-01
description	Quercetin is a kind of flavonoid compounds that comes from nature and is widely existed in the daily diet. Previous studies have found that quercetin has many effects such as anti-inflammatory, anti-oxidation and anti-cancer. Both in vivo and in vitro experiments have demonstrated that quercetin can exert anti-tumor effects by altering cell cycle progression, inhibiting cell proliferation, promoting apoptosis, inhibiting angiogenesis and metastasis progression, and affecting autophagy. This review summarizes the evidence for the pharmacological potential and inhibition of quercetin on cancers, supporting the viewpoint that quercetin should be adequately considered as a therapeutic agent against various cancers.
topic	Quercetin Cancer Inhibitory effect
url	http://www.sciencedirect.com/science/article/pii/S0753332219352266
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Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects

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